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  1. Article

    Open Access

    Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

    Epithelial–mesenchymal transition (EMT) promotes migration, invasion, and metastasis of hepatocellular carcinoma (HCC) cells. The molecular mechanisms behind EMT and metastasis in HCC remain unclear.

    Hong-Lin Luo, Tao Luo, Jun-Jie Liu, Fei-**ang Wu, Tao Bai in Cancer Cell International (2021)

  2. Article

    Open Access

    Relationship between vascular endothelial growth factor -2578C > a gene polymorphism and lung cancer risk: a meta-analysis

    Several reports were published on the relationship between the vascular endothelial growth factor (VEGF) -2578C > A gene polymorphism and lung cancer risk; however, the results are debatable. This meta-analysi...

    Hui-liu Zhao, Jia-hua Yu, Ling-sha Huang, Pei-zhang Li, Ming Lao in BMC Medical Genetics (2020)

  3. Article

    Open Access

    Distinct response of the hepatic transcriptome to Aflatoxin B1 induced hepatocellular carcinogenesis and resistance in rats

    Aflatoxin is a natural potent carcinogen and a major cause of liver cancer. However, the molecular mechanisms of hepatocellular carcinogenesis remain largely unexplored. In this study, we profiled global gene ...

    Jiejun Shi, Jiangtu He, **g Lin, **n Sun, Fenyong Sun, Chao Ou in Scientific Reports (2016)

  4. No Access

    Article

    Clinicopathological characteristics and liver stem cell marker expression in hepatocellular carcinoma involving bile duct tumor thrombi

    The aim of this study was to analyze the clinicopathological characteristics and expression of liver stem cell markers of hepatocellular carcinoma (HCC) involving bile duct tumor thrombi (BDTT). A total of 35 ...

    Ye-Bin Pang, Jian-Hong Zhong, **ao-Ling Luo, Chao Ou, Zhe Guo in Tumor Biology (2016)

  5. Article

    Open Access

    Chronic hepatitis B virus infection and occurrence of hepatocellular carcinoma in tree shrews (Tupaia belangeri chinensis)

    Hepatitis B virus (HBV) infection has been believed as a major cause of hepatocellular carcinoma (HCC) for a long time, however, the evidences of which are mostly from clinical and epidemiological investigatio...

    Chun Yang, ** Ruan, Chao Ou, Jianjia Su, Ji Cao, Chengpiao Luo in Virology Journal (2015)

  6. Article

    Open Access

    Histopathological changes in the liver of tree shrew (Tupaia belangeri chinensis) persistently infected with hepatitis B virus

    An animal model for HBV that more closely approximates the disease in humans is needed. The tree shrew (Tupaia belangeri) is closely related to primates and susceptible to HBV. We previously established that neon...

    ** Ruan, Chun Yang, Jianjia Su, Ji Cao, Chao Ou, Chengpiao Luo in Virology Journal (2013)

  7. Article

    Open Access

    Experimental chronic hepatitis B infection of neonatal tree shrews (Tupaia belangeri chinensis): A model to study molecular causes for susceptibility and disease progression to chronic hepatitis in humans

    Hepatitis B virus (HBV) infection continues to be an escalating global health problem. Feasible and effective animal models for HBV infection are the prerequisite for develo** novel therapies for this diseas...

    Qi Wang, Paul Schwarzenberger, Fang Yang, **g**g Zhang, Jianjia Su in Virology Journal (2012)

  8. No Access

    Article

    Effects of Ginkgo biloba extract on expression of biomarkers during aflatoxin B1-induced hepatocarcinogenesis in Wistar rats

    The aim of this study was to study the effect of Ginkgo biloba extract (EGb761) on metabolism of aflatoxin B1 (AFB1) in Wistar rats.

    Yanrong Hao, Jianjia Su, Chao Ou, Ji Cao in The Chinese-German Journal of Clinical Onc… (2012)