-
Article
Open AccessNear optimal minimal convex hulls of disks
The minimal convex hulls of disks problem is to find such arrangements of circular disks in the plane that minimize the length of the convex hull boundary. The mixed-integer non-linear programming model, named Mi...
-
Article
Open AccessGold nanoparticle clusters for the investigation of therapeutic efficiency against prostate cancer under near-infrared irradiation
Gold particles have been widely used in the treatment of prostate cancer due to their unique optical properties, such as their light-heat conversion in response to near-infrared radiation. Due to well-defined ...
-
Article
Open AccessSyringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence
The low response rate of current cancer immunotherapy suggests the presence of few antigen-specific T cells and a high number of immunosuppressive factors in tumor microenvironment (TME). Here, we develop a sy...
-
Chapter and Conference Paper
BULL! - The Molecular Geometry Engine Based on Voronoi Diagram, Quasi-Triangulation, and Beta-Complex
Libraries are available for the power diagram and the ordinary Voronoi diagram of points upon which application programs can be easily built. However, its counterpart for the Voronoi diagram of spheres does no...
-
Chapter and Conference Paper
BetaSCP2: A Program for the Optimal Prediction of Side-Chains in Proteins
The side-chain prediction problem (SCP-problem), is a computational problem to predict the optimal structure of proteins by finding the optimal dihedral angles. The SCP-problem is one of key computational corners...
