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Article
Open AccessPedigree analysis exploring the inconsistency between diverse phenotypes and testing criteria for germline TP53 mutations in Chinese women with breast cancer
In the present study, we addressed the inconsistency between the testing criteria and diverse phenotypes for germline TP53 mutation in patients with breast cancer in the Chinese population.
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Article
Large Eddy Simulation of Molten Steel Flow and Inclusion Transport in a New Butterfly-Type Induction Heating Tundish
In addressing the retrofitting issues of conventional non-induction heating tundish, a novel butterfly-type induction heating tundish model was devised. A three-dimensional coupled mathematical model of magnet...
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Article
Effect of Alternate Electromagnetic Stirring on Macrostructure Evolution in Thin-Slab Continuous Casting
Strand electromagnetic stirring (SEMS) is widely applied in thin-slab continuous casting to promote the equiaxed crystal ratio (ECR). However, the effects of alternate electromagnetic stirring on the evolution...
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Article
Effects of nitrogen reduction on the agronomic characteristics, quality, and water and fertilizer use efficiency of tomato (lycopersicon esculintum mill.) between drip fertigation and negative-pressure fertigation
The aim of the study is to compare the agronomic characteristics, crop quality, water use efficiency (WUE), and fertilizer use efficiency (FUE) of tomato (Lycopersicon esculintum Mill.) between drip fertigation (...
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Article
Open AccessStereotactic ablative brachytherapy versus percutaneous microwave ablation as salvage treatments for lung oligometastasis from colorectal cancer
The treatment for lung oligometastasis from colorectal cancer (CRC) remains challenging. This retrospective study aimed to compare the local tumor control, survival and procedure-related complications in CRC p...
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Article
Reliable design of humanitarian supply chain under correlated disruptions: a two-stage distributionally robust approach
This paper considers a humanitarian supply chain (SC) under uncertain correlated disruptions of facilities caused by unpredictable disasters. Prepositioned relief items in these facilities might be partly dama...
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Article
Study on the Effect of SEMS on the As-Cast Structure of Steel in Thin Slab Continuous Casting Using an Equiaxed-Columnar Solidification Model
Strand electromagnetic stirring (SEMS) is widely applied in thin slab continuous casting to improve the equiaxed crystal ratio (ECR) of steel. To provide a deeper insight into the role of SEMS in controlling t...
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Article
Effect of the Intensity of Single-Ruler Electromagnetic Braking on the Flow Pattern in a Thin-Slab Funnel Mold
Electromagnetic braking (EMBr) is critical for suppressing the turbulence in the mold and develo** a high-speed thin-slab continuous casting technology. The main problem is that the relationship between EMBr...
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Article
Open AccessNomogram prediction of the 70-gene signature (MammaPrint) binary and quartile categorized risk using medical history, imaging features and clinicopathological data among Chinese breast cancer patients
The 70-gene signature (70-GS, MammaPrint) test has been recommended by the main guidelines to evaluate prognosis and chemotherapy benefit of hormonal receptor positive human epidermal receptor 2 negative (HR +...
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Article
FDNet: A Deep Learning Approach with Two Parallel Cross Encoding Pathways for Precipitation Nowcasting
With the goal of predicting the future rainfall intensity in a local region over a relatively short period time, precipitation nowcasting has been a long-time scientific challenge with great social and economi...
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Article
An Improved Columnar Solidification Model Coupled With Anisotropic Mush Permeability
To get a basic understanding of the solute transportation and chemical inhomogeneity in directional columnar structures, the anisotropic permeability law was integrated into a volume-averaged columnar solidifi...
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Article
G6PD activation in TNBC cells induces macrophage recruitment and M2 polarization to promote tumor progression
Glucose-6-phosphate dehydrogenase (G6PD) is involved in triple-negative breast cancer (TNBC) progression. Metabolic crosstalk between cancer cells and tumor-associated macrophages mediates tumor progression in...
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Article
Open AccessA reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors
BRAFV600E mutation confers a poor prognosis in metastatic colorectal cancer (CRC) despite combinatorial targeted therapies based on the latest understanding of signaling circuitry. To identify parallel resistance...
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Article
Open AccessCorrection to: Hemorrhagic fever with renal syndrome caused by destruction of residential area of rodent in a construction site: epidemiological investigation
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Article
Open AccessHemorrhagic fever with renal syndrome caused by destruction of residential area of rodent in a construction site: epidemiological investigation
An outbreak of hemorrhagic fever with renal syndrome (HFRS), caused by a Hantavirus, affected nine adult males in the southwest area of **’an in November 2020 was analyzed in this study.
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Article
Open AccessRationale and design of a phase II trial of pyrotinib in combination with nab-paclitaxel as adjuvant therapy for N0/N1mi, HER2 + early breast cancer (PHAEDRA)
The de-escalation treatment in patients with low-risk HER2-positive early breast cancer (eBC) is an attractive strategy to avoid unnecessary treatment and improve the quality of life of patients. Pyrotinib, a ...
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Article
Breast-conserving therapy for breast cancer with BRCA mutations: a meta-analysis
BRCA1/2 mutated breast cancer accounts for 3 to 12% of all women with breast cancer and significantly increases the lifetime risk of breast cancer. However, the optimal local treatment for breast cancer with B...
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Chapter and Conference Paper
Effect of Grouting Defect Sleeve on Seismic Performance of Concrete Column
The development of assembly construction technology has become an inevitable way for the transformation and upgrading of China’s construction industry. However, in the development process, the grouting sleeve ...
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Chapter and Conference Paper
Ships Target Detection on Water Based on Improved Faster RCNN
The intelligent research of watercraft detection is of great significance to the construction of marine transportation industry. Based on the Faster RCNN algorithm, this paper proposes a watercraft target dete...
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Chapter and Conference Paper
Optimally Integrating Ad Auction into E-Commerce Platforms
Advertising becomes one of the most popular ways of monetizing an online transaction platform. Usually, sponsored advertisements are posted on the most attractive positions to enhance the number of clicks. How...
