-
Article
Open AccessLong-term outcomes of CNS WHO grade 2 oligodendroglioma in adult patients: a single-institution experience
Oligodendrogliomas (ODGs) are a subtype of diffuse lower-grade gliomas with overall survival of > 10 years. This study aims to analyze long-term outcomes and identify prognostic factors in patients with WHO gr...
-
Article
Prediction of pseudoprogression in post-treatment glioblastoma using dynamic susceptibility contrast-derived oxygenation and microvascular transit time heterogeneity measures
To evaluate the added value of MR dynamic susceptibility contrast (DSC)-perfusion-weighted imaging (PWI)-derived tumour microvascular and oxygenation information with cerebral blood volume (CBV) to distinguish...
-
Article
Open AccessExploring prognostic factors and treatment strategies for long-term survival in pleomorphic xanthoastrocytoma patients
Pleomorphic xanthoastrocytomas (PXA) are rare, accounting for < 1% of all astrocytomas. Literature on the clinical course and treatment outcomes of PXAs is limited. The study aimed to determine prognosis and t...
-
Article
Defining subventricular zone involvement to predict the survival of patients in isocitrate dehydrogenase-wild type glioblastoma: validation in a prospective registry
The prognostic value of subventricular zone distance (SVD) is unclear because of different definitions and lack of evaluation of clinical survival models. The aim of this study was to define SVD and evaluate i...
-
Article
Open AccessProteomic analysis predicts anti-angiogenic resistance in recurred glioblastoma
Recurrence is common in glioblastoma multiforme (GBM) because of the infiltrative, residual cells in the tumor margin. Standard therapy for GBM consists of surgical resection followed by chemotherapy and radio...
-
Article
Is the cochleovestibular nerve function affected in patients with hemifacial spasm?
Hemifacial spasm (HFS) is a motor disorder caused by the vascular compression of the facial nerve in the posterior fossa. The cochleovestibular nerve is close to the facial nerve and shares the same entry to t...
-
Article
Open AccessDifferences in stromal component of chordoma are associated with contrast enhancement in MRI and differential gene expression in RNA sequencing
Chordoma is a malignant bone neoplasm demonstrating notochordal differentiation and it frequently involves axial skeleton. Most of chordomas are conventional type with varying amount of myxoid stroma. Previous...
-
Article
Open AccessThirty-year clinical experience in gamma knife radiosurgery for trigeminal schwannomas
We aimed to evaluate the radiographic and clinical outcomes after gamma knife radiosurgery (GKRS) for trigeminal schwannomas (TSs). A total of 87 patients who underwent GKRS for TSs between 1990 and 2020 were ...
-
Article
Open AccessPedicled frontal periosteal rescue flap via eyebrow incision for skull base reconstruction (SevEN-002)
Cerebrospinal fluid (CSF) leakage is one of the major complications after endoscopic endonasal surgery. The reconstructive nasoseptal flap is widely used to repair CSF leakage. However, it could not be utilize...
-
Article
The role of apparent diffusion coefficient as a predictive factor for tumor recurrence in patients with cerebellopontine angle epidermoid tumor
Intracranial epidermoid tumors are slowly growing benign tumors, but due to adjacent critical neurovascular structures, surgical resection is challenging, with the risk of recurrence. The apparent diffusion co...
-
Article
Clinical applications of the endoscopic transorbital approach for various lesions
The endoscopic transorbital approach (ETOA) was recently added to the neurosurgical armamentarium. Although this approach could result in less injury to normal brain tissue, shorter operation times, and smalle...
-
Article
Differences in surgical outcome between petroclival meningioma and anterior petrous meningioma
Petroclival meningiomas (PC MNGs) and anterior petrous meningiomas (AP MNGs) have similar locations. However, these are different tumors clearly divided by the trigeminal nerve. There has never been a study on...
-
Article
Open AccessThe behavior of residual tumors following incomplete surgical resection for vestibular schwannomas
The management of vestibular schwannoma (VS) with residual tumor following incomplete resection remains controversial and little is known regarding postoperative tumor volume changes. The behavior of residual ...
-
Article
Open AccessOptimization of orbital retraction during endoscopic transorbital approach via quantitative measurement of the intraocular pressure – [SevEN 006]
Increased use of the transorbital approach (TOA) warrants greater understanding of the risk of increased intraocular pressure (IOP) and intraorbital pressure (IORP) due to orbital compression. We aimed to inve...
-
Article
Open AccessApparent diffusion coefficient as a prognostic factor in clival chordoma
Clival chordoma is a rare disease with high recurrence rates even after a combination of surgical resection and radiotherapy. Apparent diffusion coefficient (ADC) has been used to evaluate aggressive features ...
-
Article
Radiosurgery vs. microsurgery for newly diagnosed, small petroclival meningiomas with trigeminal neuralgia
Trigeminal neuralgia (TN) is an excruciating pain that can occur with petroclival meningiomas (PCMs). Gamma knife radiosurgery (GKRS) is an appealing option for small PCMs, but the role of microsurgery (MS) co...
-
Article
Open AccessAnterior skull base reconstruction using nasoseptal flap: cadaveric feasibility study and clinical implication [SevEN-001]
Pedicled nasoseptal flap (PNSF) has significantly improved the surgical outcomes of endoscopic endonasal approach (EEAs) by reducing cerebrospinal fluid (CSF) leakage. The purpose of this study is to assess th...
-
Article
Biportal endoscopic transorbital approach: a quantitative anatomical study and clinical application
We devised a biportal endoscopic transorbital approach (BiETOA) to gain surgical freedom by making a port for the endoscope and investigated the benefits and limitations of BiETOA.
-
Article
Open AccessAssociation between survival and levetiracetam use in glioblastoma patients treated with temozolomide chemoradiotherapy
This study was conducted to assess whether levetiracetam (LEV) affects the survival of patients with glioblastoma (GBM) treated with concurrent temozolomide (TMZ) chemotherapy. To this end, from 2004 to 2016, ...
-
Article
Lateral supraorbital versus pterional approach for parachiasmal meningiomas: surgical indications and esthetic benefits
The lateral supraorbital (LSO) approach is a minimally invasive modification of the pterional approach. The authors assess the surgical indications and esthetic benefits of the LSO approach in comparison with ...
