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Chapter and Conference Paper
Axonal Transport Defects in Retinal Ganglion Cell Diseases
For the survival and maintenance of retinal ganglion cells (RGCs), axonal transportation is fundamental. Axonal transportation defects can cause severe neuropathies leading to neuronal loss. Axonal defects u...
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Protocol
A Simple Guide for Generating BAC Transgenic Animals for Retinal Research
Bacterial artificial chromosomes (BACs) are genomic tools that can carry several hundred kilobases of exogenous genomic material. This allows to incorporate sufficiently large DNA stretches to include most if ...
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Article
Open AccessExpression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism
Photoreceptor degeneration is a main hallmark of many blinding diseases making protection of photoreceptors crucial to prevent vision loss. Thus, regulation of endogenous neuroprotective factors may be key for...
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Chapter and Conference Paper
Leukemia Inhibitory Factor Signaling in Degenerating Retinas
Degeneration of cells in the retina is a hallmark of various inherited and acquired blinding diseases in humans. One of the most challenging problems to establish successful treatments for these diseases is to...