Skip to main content

and
  1. No Access

    Article

    Phenolic Metabolites Modulate Cardiomyocyte Beating in Response to Isoproterenol

    Cardiovascular disease (CVD) is a public health concern, and the third cause of death worldwide. Several epidemiological studies and experimental approaches have demonstrated that consumption of polyphenol-enr...

    Daniela Dias-Pedroso, Joel Guerra, Andreia Gomes, Carole Oudot in Cardiovascular Toxicology (2019)

  2. No Access

    Reference Work Entry In depth

    ANT

    Grégory Tufo, Lorenzo Galluzzi, Guido Kroemer in Encyclopedia of Signaling Molecules (2018)

  3. No Access

    Chapter

    Mitochondrial Regulation of Cell Death

    Mitochondria are multifaceted organelles exerting vital as well as lethal functions within eukaryotic cells. When fueled with substrates and oxygen, mitochondria govern metabolic pathways, regulate calcium flu...

    Dawei Liu, Jean-Luc Perfettini in Mitochondrial Biology and Experimental The… (2018)

  4. No Access

    Reference Work Entry In depth

    Mitochondrial Membrane Permeabilization in Apoptosis

    Catherine Brenner in Encyclopedia of Cancer (2017)

  5. No Access

    Living Reference Work Entry In depth

    ANT

    Grégory Tufo, Lorenzo Galluzzi, Guido Kroemer in Encyclopedia of Signaling Molecules

  6. No Access

    Protocol

    Enzymatic Assays for Probing Mitochondrial Apoptosis

    Isolated mitochondria are an invaluable analytical tool to probe mitochondrial function and evaluate apoptosis induction via the so-called mitochondrial pathway. Irrespective of their tissue origin (e.g., hear...

    Zhenyu Wang, Claire Nicolas, Rodolphe Fischmeister in Mitochondrial Medicine (2015)

  7. No Access

    Living Reference Work Entry In depth

    Mitochondrial Membrane Permeabilization in Apoptosis

    Catherine Brenner in Encyclopedia of Cancer

  8. No Access

    Article

    Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

    A high resistance and heterogeneous response to conventional anti-cancer chemotherapies characterize malignant cutaneous melanoma, the most aggressive and deadly form of skin cancer. Withaferin A (WFA), a with...

    Eleonore Mayola, Cindy Gallerne, Davide Degli Esposti, Cecile Martel in Apoptosis (2011)

  9. No Access

    Reference Work Entry In depth

    Mitochondrial Membrane Permeabilization in Apoptosis

    Catherine Brenner in Encyclopedia of Cancer (2011)

  10. No Access

    Article

    A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice

    Dengue viruses belong to the Flavivirus family and are responsible for hemorrhagic fever in Human. Dengue virus infection triggers apoptosis especially through the expression of the small membrane (M) protein....

    Magali Brabant, Ludwig Baux, Richard Casimir, Jean Paul Briand in Apoptosis (2009)

  11. No Access

    Reference Work Entry In depth

    Mitochondrial Membrane Permeabilization in Apoptosis

    Catherine Brenner in Encyclopedia of Cancer (2009)

  12. Article

    Methods for the assessment of mitochondrial membrane permeabilization in apoptosis

    Mitochondrial membrane permeabilization (MMP) is considered as the “point-of-no-return” in numerous models of programmed cell death. Indeed, mitochondria determine the intrinsic pathway of apoptosis, and play ...

    Lorenzo Galluzzi, Naoufal Zamzami, Thibault de La Motte Rouge in Apoptosis (2007)

  13. No Access

    Article

    Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria

    The human probiotic Propionibacterium freudenreichii kills colorectal adenocarcinoma cells through apoptosis in vitro via its metabolites, the short chain fatty acids (SCFA), acetate and propionate. However, the ...

    Annaïg Lan, Dominique Lagadic-Gossmann, Christophe Lemaire, Catherine Brenner in Apoptosis (2007)

  14. No Access

    Article

    Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis

    In the present study, the toxicity of yperite, SM, and its structural analogue mechlorethamine, HN2, was investigated in a human bronchial epithelial cell line 16HBE. Cell detachment was initiated by caspase-2...

    Matthieu Sourdeval, Christophe Lemaire, Aurélien Deniaud, Laurent Taysse in Apoptosis (2006)

  15. No Access

    Article

    Insights into the Mitochondrial Signaling Pathway: What Lessons for Chemotherapy?

    Mitochondria are potent integrators/coordinators of apoptosis signaling pathways. Indeed, under physiological conditions, the initiation of apoptosis leads to the accumulation of second messengers that converg...

    Catherine Brenner, Morgane Le Bras, Guido Kroemer in Journal of Clinical Immunology (2003)