8 Result(s)
within
Carmelo Carmona-Rivera
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Article
Open AccessNeutrophils in Inflammatory Bone Diseases
In this review, we summarize the current evidence that suggests that neutrophils play a key role in facilitating damage to local bone structures.
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Article
Open AccessConstitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome
Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases; pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. Here we...
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Article
Open AccessApoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway
Most tumor cells undergo apoptosis in circulation and at the metastatic organ sites due to host immune surveillance and a hostile microenvironment. It remains to be elucidated whether dying tumor cells have a ...
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Article
Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides
Cleavage products of the proteasome are profiled by mass spectrometry.
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Article
Open AccessDEK-targeting DNA aptamers as therapeutics for inflammatory arthritis
Novel therapeutics are required for improving the management of chronic inflammatory diseases. Aptamers are single-stranded RNA or DNA molecules that have recently shown utility in a clinical setting, as they ...
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Article
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
Lupus-like disease is driven by NETs enriched in mitochondrial DNA.
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Protocol
Detection of SLE Antigens in Neutrophil Extracellular Traps (NETs)
Neutrophils are sentinel cells of the innate immune system with a primary role of clearing extracellular pathogens. The release of weblike structures decorated with granular proteins called neutrophil extracel...
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Article
Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity
Recent studies have renewed the interest on the potential role that neutrophils play in the development of systemic lupus erythematosus (SLE) and other autoimmune conditions. A distinct subset of proinflammato...
