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Article
Open AccessUse of computed tomography coronary calcium score for prediction of cardiovascular events in cancer patients: a retrospective cohort analysis
CT- coronary calcium score, is one of the most studied and widely available modalities in cardiovascular medicine. Coronary artery calcium score (CACS) is an established predictor of coronary artery disease. T...
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Article
Open AccessUnveiling RCOR1 as a rheostat at transcriptionally permissive chromatin
RCOR1 is a known transcription repressor that recruits and positions LSD1 and HDAC1/2 on chromatin to erase histone methylation and acetylation. However, there is currently an incomplete understanding of RCOR1...
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Article
Open AccessRevealing RCOR2 as a regulatory component of nuclear speckles
Nuclear processes such as transcription and RNA maturation can be impacted by subnuclear compartmentalization in condensates and nuclear bodies. Here, we characterize the nature of nuclear granules formed by R...
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Article
Open AccessOncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers
The pervasive role of microRNAs (miRNAs) in cancer pathobiology drives the introduction of new drug development approaches such as miRNA inhibition. In order to advance miRNA-therapeutics, meticulous screening...
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Article
Open AccessA sweetpotato gene index established by de novo assembly of pyrosequencing and Sanger sequences and mining for gene-based microsatellite markers
Sweetpotato (Ipomoea batatas (L.) Lam.), a hexaploid outcrossing crop, is an important staple and food security crop in develo** countries in Africa and Asia. The availability of genomic resources for sweetpota...
