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  1. Article

    Open Access

    Three-dimensional vascular microenvironment landscape in human glioblastoma

    The cellular complexity of glioblastoma microenvironments is still poorly understood. In-depth, cell-resolution tissue analyses of human material are rare but highly necessary to understand the biology of this...

    George P. Cribaro, Elena Saavedra-López… in Acta Neuropathologica Communications (2021)

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    Chapter

    Increase of Secondary Processes of Microglial and Astroglial Cells After MPTP-Induced Degeneration in Substantia Nigra Pars Compacta of Non Human Primates

    Nigral dopaminergic areas from Parkinsonian patients show an increase of reactive astrocytes and active microglia. The reaction of these two cell types is a clear evidence of inflammatory response associated w...

    Carlos Barcia, Carmen M. Ros… in Birth, Life and Death of Dopaminergic Neur… (2009)

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    Chapter

    Inflammatory Response in Parkinsonism

    Inflammatory responses have been proposed as important factors in dopaminergic neuro-degeneration in Parkinsonism. Increasing evidence suggests that the alteration of the glial microenvironment induced by neur...

    Carlos Barcia, Francisco Ros… in Birth, Life and Death of Dopaminergic Neur… (2009)

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    Chapter and Conference Paper

    Modulatory Role of NK1 Receptors in the Basal Ganglia. Studies in NK1-/- Mice

    Laura Turpín, Jorge Boronat, Carlos Barcia, María Gómez… in The Basal Ganglia VIII (2005)

  5. No Access

    Article

    Parkinson's disease and inflammatory changes

    In 1988 McGeer and colleagues (Neurology 38, 1285–91) observed an activation of the microglia in substantia nigrapars compacta (SNpc) and striatum of brains from patients with Parkinson's disease. In the years th...

    Carlos Barcia, Andrés Fernández Barreiro, Máximo Poza… in Neurotoxicity Research (2003)

  6. No Access

    Chapter

    Blood Vessels And Neurodegeneration In Parkinson’s Disease

    Parkinson’s disease (PD) is characterised by a differential vulnerability of dopaminergic neurons in the mesencephalon. The loss is severe in the substantia nigra pars compacta (SNpc) (85-90%), intermediate in th...

    Carlos Barcia, Angel Sánchez-Bahillo, Victor Bautista-Hernández… in The Basal Ganglia VII (2002)