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  1. No Access

    Article

    Puerarin Alleviates Lipopolysaccharide-Induced Myocardial Fibrosis by Inhibiting PARP-1 to Prevent HMGB1-Mediated TLR4-NF-κB Signaling Pathway

    Myocardial fibrosis (MFs) is a crucial pathological process that results in cardiac failure in the development of multiple cardiovascular diseases. Puerarin could reportedly be used to treat a variety of cardi...

    Shu-Yuan Ni, **ng-Long Zhong, Ze-Hua Li, Dong-Jian Huang… in Cardiovascular Toxicology (2020)

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    Article

    Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress

    This study aimed to investigate the anti-oxidant and anti-hypertrophic effects of puerarin-7-O-glucuronide, a water-soluble puerarin metabolite. The anti-oxidant effects of puerarin-7-O-glucuronide were assessed ...

    Ning Hou, Bin Cai, Cai-Wen Ou… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2017)