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Article
Open AccessPerformances of a new generation tracking detector: the MEG II cylindrical drift chamber
The cylindrical drift chamber is the most innovative part of the MEG II detector, the upgraded version of the MEG experiment. The MEG II chamber differs from the MEG one because it is a single volume cylindric...
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Article
Open AccessA search for \(\upmu ^+ \rightarrow \textrm{e}^+ \upgamma \) with the first dataset of the MEG II experiment
The MEG II experiment, based at the Paul Scherrer Institut in Switzerland, reports the result of a search for the decay $$\upmu ^+ \rightarrow...
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Article
COVID-19 therapy optimization by AI-driven biomechanical simulations
The COVID-19 disease causes pneumonia in many patients that in the most serious cases evolves into the Acute Distress Respiratory Syndrome (ARDS), requiring assisted ventilation and intensive care. In this con...
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Article
Open AccessSearch for lepton flavour violating muon decay mediated by a new light particle in the MEG experiment
We present the first direct search for lepton flavour violating muon decay mediated by a new light particle X, $$\upmu ^+ \rightarrow \mathrm ...
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Article
Open AccessThe design of the MEG II experiment
The MEG experiment, designed to search for the \({\mu ^+ \rightarrow \hbox {e}^+ \gamma }\) ...
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Article
Open AccessThe quest for \(\mu \rightarrow e \gamma \) and its experimental limiting factors at future high intensity muon beams
The search for the lepton flavor violating decay \(\mu ^+ \rightarrow e^+ \gamma \) ...
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Article
Open AccessSearch for the lepton flavour violating decay \(\mu ^+ \rightarrow \mathrm {e}^+ \gamma \) with the full dataset of the MEG experiment
The final results of the search for the lepton flavour violating decay $$\mathrm {\mu }^+ \rightarrow \mathrm {e}^+ \mathrm {\gamma }$...
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Article
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency
Most of the anaplastic large-cell lymphoma (ALCL) cases carry the t(2;5; p23;q35) that produces the fusion protein NPM-ALK (nucleophosmin-anaplastic lymphoma kinase). NPM-ALK-deregulated kinase activity drives...
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Article
Open AccessMuon polarization in the MEG experiment: predictions and measurements
The MEG experiment makes use of one of the world’s most intense low energy muon beams, in order to search for the lepton flavour violating process ...
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Article
Open AccessMeasurement of the radiative decay of polarized muons in the MEG experiment
We studied the radiative muon decay \({\upmu }^{+} \rightarrow \mathrm {e}^{+} {\upnu }\bar{{\upnu }}{\upgamma }\) ...
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Open AccessThe Physics of the B Factories
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Open AccessA novel radioguided surgery technique exploiting β− decays
The background induced by the high penetration power of the radiation is the main limiting factor of the current radio-guided surgery (...
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Article
Open AccessThe MEG detector for μ +→e+ γ decay search
The MEG (Mu to Electron Gamma) experiment has been running at the Paul Scherrer Institut (PSI), Switzerland since 2008 to search for the decay μ +→e+ γ by using one of the most int...
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Article
Open AccessThe EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1
In non-small cell lung cancer (NSCLC), receptor tyrosine kinases (RTKs) stand out among causal dominant oncogenes, and the ablation of RTK signaling has emerged as a novel tailored therapeutic strategy. Noneth...
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BRAF gene is not mutated in plasma cell leukemia and multiple myeloma
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Detection of minimal residual disease by real-time PCR can be used as a surrogate marker to evaluate the graft-versus-myeloma effect after allogeneic stem cell transplantation
Allogeneic stem cell transplantation (allo-SCT) is an effective and potentially curative treatment for some cases of multiple myeloma (MM). The curative efficacy of allo-SCT may be largely attributed to its im...
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Article
A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors
Several methods have been developed for the detection of minimal residual disease (MRD) in B cell tumors. Chromosomal translocations or the rearrangement of the immunoglobulin heavy chain (IgH) and T cell rece...
