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Chapter and Conference Paper
Prognostic Significance of Exposure to Intermediate-Dose Methotrexate in Children with Standard Risk ALL: The COALL 82/85 Experience
Methotrexate is being widely used in doses ranging from 500 to 2 000 mg administered as prolonged infusion over 12–36 h followed by leucovorin rescue to consolidate remission of acute lymphoblastic leukemia [1...