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9 Result(s)

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  1. Article

    Open Access

    Antipsychotic drug-induced neutropenia: results from the AMSP drug surveillance program between 1993 and 2016

    Neutropenia and agranulocytosis (N&A) are relatively rare, but potentially fatal adverse drug reactions (ADR). This study presents cases of N&A related to one or more antipsychotic drugs (APDs) in psychiatric ...

    Catherine Glocker, R. Grohmann, G. Burkhardt, J. Seifert… in Journal of Neural Transmission (2023)

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  2. Article

    Open Access

    Galactorrhea during antipsychotic treatment: results from AMSP, a drug surveillance program, between 1993 and 2015

    Galactorrhea is a well-known adverse drug reaction (ADR) of numerous antipsychotic drugs (APD) and is often distressing for those affected. Methodological problems in the existing literature make it difficult ...

    C. Glocker, R. Grohmann, R. Engel… in European Archives of Psychiatry and Clinic… (2021)

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  3. No Access

    Article

    Depressive Kernsymptome

    Unter Kernsymptomen einer Depression versteht man eine Reihe typischer psychischer und somatischer Symptome, die häufig gemeinsam mit psychomotorischen und kognitiven Störungen auftreten. Die aktuelle diagnost...

    Dr. J. Damm, D. Eser, C. Schüle, H.-J. Möller, R. Rupprecht, T.C. Baghai in Der Nervenarzt (2009)

  4. No Access

    Article

    Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression

    The serotonergic system is involved in the pathophysiology of major depression as well as in the early central nervous system development and adult neuroplasticity. The aim of the study was to examine in 77 pa...

    T Frodl, N Koutsouleris, R Bottlender, C Born, M Jäger… in Molecular Psychiatry (2008)

  5. No Access

    Article

    Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3α-hydroxysteroid dehydrogenase activity

    Concentrations of 3α-reduced neuroactive steroids are altered in depression and normalize after antidepressant pharmacotherapy with selective serotonin re-uptake inhibitors (SSRIs). We investigated the impact of ...

    C Schüle, E Romeo, D P Uzunov, D Eser, F di Michele, T C Baghai… in Molecular Psychiatry (2006)

  6. No Access

    Article

    SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

    Tryptophan hydroxylase (TPH), being the rate-limiting enzyme in the biosynthesis of serotonin plays a major role as candidate gene in several psychiatric disorders. Recently, a second TPH isoform (TPH2) was id...

    P Zill, T C Baghai, P Zwanzger, C Schüle, D Eser, R Rupprecht… in Molecular Psychiatry (2004)

  7. Article

    Effects of Alprazolam on Cholecystokinin-Tetrapeptide-Induced Panic and Hypothalamic–Pituitary–Adrenal-Axis Activity: A Placebo-Controlled Study

    Cholecystokinin-tetrapeptide (CCK-4) induces panic attacks both in patients with panic disorder (PD) and healthy volunteers. It has been shown that panic elicited by CCK-4 is improved after treatment with anti...

    P Zwanzger, D Eser, S Aicher, C Schüle, T C Baghai, F Padberg… in Neuropsychopharmacology (2003)

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  8. No Access

    Article

    Hypericum-perforatum-Extrakt bei der Behandlung leichter bis mittelschwerer Depressionen Klinische und pharmakologische Aspekte

    Seit vielen Jahren werden Hyperikumextrakte in der Behandlung depressiver Erkrankungen eingesetzt. Der therapeutische Einsatz dieser Extrakte wurde hierbei lange Zeit vorwiegend mit der klinischen Evidenz ihre...

    G. Laakmann, G. Jahn, C. Schüle in Der Nervenarzt (2002)

  9. No Access

    Article

    Possible influence of the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene on theraputic outcome in affective disorders

    T C Baghai, C Schüle, P Zwanzger, C Minov, M J Schwarz, S de Jonge… in Molecular Psychiatry (2001)