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Article
Open AccessToxicity with small molecule and immunotherapy combinations in non-small cell lung cancer
Treatment stratification in stage IV NSCLC is guided by identification of oncogene driver mutations. Actionable mutations with current licenced therapeutic agents include epidermal growth factor receptor (EGFR...
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Article
Open AccessVimentin and Ki67 expression in circulating tumour cells derived from castrate-resistant prostate cancer
High circulating tumor cell (CTC) counts are associated with poor prognosis in advanced prostate cancer, and recently CTC number was suggested to be a surrogate for survival in metastatic castrate-resistant pr...
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Article
Regulation of mitosis and taxane response by Daxx and Rassf1
Current theories suggest that mitotic checkpoint proteins are essential for proper cellular response to taxanes, a widely used family of chemotherapeutic compounds. We recently showed that absence or depletion...