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    Article

    Effects of low-dose naloxone on opioid therapy in pediatric patients: a retrospective case-control study

    To develop novel therapies that prevent opioid tolerance in critically ill children we examined the effects of low-dose naloxone infusions on patients' needs for analgesia or sedation.

    C. L. S. Cheung, M. van Dijk, J. W. Green, D. Tibboel… in Intensive Care Medicine (2007)