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Article
Gut microbiota, a potential cause of higher insulin sensitivity in children with Prader–Willi syndrome
Obesity is the main driving factor for comorbidities in Prader–Willi syndrome (PWS) patients due to overeating behaviors. The gut microbiota has been implicated in the etiology of obesity and associated comorb...
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Article
Open AccessSonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth
Sonic hedgehog (Shh) functions as a conserved morphogen in the development of various organs in metazoans ranging from Drosophila to humans. Here, we have investigated the potential roles and underlying mechanism...
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Article
Cranio-osteoarthropathy: a rare variant of hypertrophic osteoarthropathy
To highlight the clinical features and diagnosis of cranio-osteoarthropathy, an extremely rare disease.
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Article
Plasma ghrelin levels and polymorphisms of ghrelin gene in Chinese obese children and adolescents
To evaluate the role of fasting plasma ghrelin levels [ln(ghrelin)] and polymorphisms of ghrelin gene in Chinese obese children.
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Article
Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome
Objective: To report a case of type 1 diabetes mellitus (T1DM) in a child with phenobarbital hypersensitivity syndrome with an emphasis on the clinical presentation, diagnostic modalities...
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Article
Prevalence of the metabolic syndrome in Zhejiang Chinese obese children and adolescents and the effect of metformin combined with lifestyle intervention
We aimed to evaluate the prevalence of metabolic syndrome (MS) in a group of obese children and adolescents in Zhejiang in the south of China, and to compare risk factors such as insulin resistance, adiponecti...