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Article
Open AccessGut microbiota and immune profiling of microbiota-humanised versus wildtype mouse models of hepatointestinal schistosomiasis
Mounting evidence of the occurrence of direct and indirect interactions between the human blood fluke, Schistosoma mansoni, and the gut microbiota of rodent models raises questions on the potential role(s) of the...
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Article
Open AccessEffektivität von Eslicarbazepinacetat in 2 unterschiedlichen Kohorten von Patienten mit Epilepsie in der klinischen Praxis – Ergebnisse einer retrospektiven Datensammlung aus 2 Epilepsiezentren in Deutschland
Eslicarbazepinacetat (ESL) ist ein Antiepileptikum der dritten Generation, das in der EU seit 2009 als Zusatztherapie und seit 2017 als Monotherapie fokaler Anfälle zugelassen ist.
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Article
Quantitative electroencephalography supports diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy
Long-term treatment of multiple sclerosis with natalizumab (NTZ) carries the risk of a devastating complication in the form of an encephalopathy caused by a reactivation of a latent John Cunningham virus infec...
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Article
Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation
The frequency of poor outcomes in relapsed leukemia patients underscores the need for novel therapeutic approaches. The Food and Drug Administration-approved immunosuppressant FTY720 limits leukemia progressio...
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Article
Sportbootführerschein bei Epilepsie
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Chapter
Time-Scale-Based Segmentation for Degraded PCG Signals Using NMF
This article deals with the challenging problem of segmenting narrowly spaced cardiac events (S1 and S2) in noisy phonocardiogram (PCG) signals by using a novel application of NMF based on time-scale approach....
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Article
Leben mit chronischer spinaler Muskelatrophie
Eines der höchsten Ziele der individuellen menschlichen Entwicklung ist es, erwachsen zu werden, sein Leben selbstständig und eigenverantwortlich in die Hand zu nehmen und vielleicht sogar seinen Beitrag für d...
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Chapter and Conference Paper
Surface Generation Process with Consideration of the Balancing State in Diamond Machining
In order to manufacture optical components or mechanical parts with high requirements regarding surface quality, diamond machining is frequently applied. Nevertheless, to achieve the desired surface quality, t...
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Chapter and Conference Paper
Adaptive Finite Elements and Mathematical Optimization Methods
This chapter focuses on the topics of mathematical research in the priority program and on the application of the results to engineering problems. First, a posteriori estimates and adaptive methods based on th...
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Article
Spectroscopy and laser operation of Nd-doped mixed sesquioxides (Lu1−x Sc x )2O3
We report on crystal growth, spectroscopic investigations, crystal field tuning, and laser experiments of neodymium doped mixed sesquioxides (Lu1−x Sc x )2O3. Cry...
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Article
Bumetanid als antiepileptogene Strategie?
Eine Herausforderung in der Epilepsieforschung ist es, Strategien zu finden, die verhindern, dass es nach einem Hirninsult zur Entstehung einer Epilepsie kommt (Antiepileptogenese). Die Voraussetzung für eine ...
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Article
Using the CeSiC material for the WSO-UV spectrographs
The World Space Observatory Ultraviolet (WSO-UV) is a multi-national project lead by the Russian Federal Space Agency (Roscosmos) with the objective of high performance observations in the ultraviolet range. The ...
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Article
Photoconductivity in Yb-doped oxides at high excitation densities
Photoconductivity has been found in the dielectric laser materials Yb3+:YAG and Yb3+:Lu2O3 under 940 nm irradiation with an unexpected high photocurrent up to several 100 nanoampères. The nonlinear intensity depe...
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Chapter and Conference Paper
Localization of Heart Sounds Based on S-Transform and Radial Basis Function Neural Network
This paper presents an original method for heart sounds localization based on S-Transform and radial basis function neural network (SRBF). The S-Transform is used to extract the features of heart sound. These ...
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Article
Open AccessDrug induced modulation of T cell activation and differentiation in atopic dermatitis patients
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Article
Weichteilemphysem ungewöhnlichen Ausmaßes
Streptococcus agalactiae, bekannt als Meningitis- und Sepsiserreger bei Neugeborenen, gewinnt als Verursacher schwerer, invasiver Infektionen bei Erwachsenen zunehmend an Bedeutung. Die v...
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Article
Intensified Strategies to Control Vancomycin-Resistant Enterococci in Immunocompromised Patients
Increasing colonization and infection with vancomycin-resistant enterococci (VRE) in immunocompromised patients are associated with increased mortality. Despite contact precautions for VRE control, rapid limit...
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Article
Postoperative Wundinfektionen
Die Entstehung der meisten postoperativen Wundinfektionen lässt sich auf das Zeitintervall des Aufenthalts des Patienten in einem bestimmten Krankenhausbereich – den OP-Saal – zurückführen. Deshalb wird ihre P...
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Article
Self-Consistent Analysis of the Spatial Relaxation of a Disturbed Neon Glow Discharge
The response of a neon glow discharge plasma on a disturbance caused by a floating Langmuir probe is studied by a fully self-consistent, spatially one-dimensional hybrid method as well as by measurements. The ...
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Article
„Spontaner“ Gasbrand mit Kompartmentsyndrom bei einem diabetischen Patienten
Spontane Gasbrandinfektionen, ausgelöst durch Clostridium septicum, treten gehäuft bei Patienten mit bestimmten disponierenden, nicht selten malignen Grunderkrankungen auf. Die Kasuistik zeigt beispielhaft die As...
