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Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

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  1. Article

    E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35

    The transcription factor E2F1 has a key function during S phase progression and apoptosis. It has been well-demonstrated that the apoptotic function of E2F1 involves its ability to transactivate pro-apoptotic ...

    G Merdzhanova, V Edmond, S De Seranno, A Van den Broeck… in Cell Death & Differentiation (2008)

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  2. Article

    E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIPshort

    E2F1 is a transcription factor that plays a well-documented role during S phase progression and apoptosis. We had previously postulated that the low level of E2F1 in primary lung adenocarcinoma contributes to ...

    C Salon, B Eymin, O Micheau, L Chaperot, J Plumas… in Cell Death & Differentiation (2006)

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