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  1. Article

    Open Access

    Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways

    Rhabdomyosarcoma (RMS) is the most frequent form of pediatric soft-tissue sarcoma. It is divided into two main subtypes: ERMS (embryonal) and ARMS (alveolar). Current treatments are based on chemotherapy, surg...

    J. Vial, P. Huchedé, S. Fagault, F. Basset, M. Rossi, J. Geoffray… in Cell Death Discovery (2020)

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  2. Article

    Caspase-1 activation of caspase-6 in human apoptotic neurons

    Active caspase-6 (Csp-6) induces cell death in primary cultures of human neurons and is abundant in the neuropathological lesions of Alzheimer's disease. However, the mode of Csp-6 activation is not known. Her...

    H Guo, D Pétrin, Y Zhang, C Bergeron, C G Goodyer… in Cell Death & Differentiation (2006)

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  3. No Access

    Chapter

    Presenilin Proteins and the Pathogenesis of Early-Onset Familial Alzheimer’s Disease: β-Amyloid Production and Parallels to Prion Diseases

    In contrast to rare mutations in the amyloid presursor protein (APP) gene, missense mutations in the presenilin 1 (PS1) and presenilin 2 (PS2) genes, on chromosomes 14 and 1 respectively, are the most common c...

    D. Westaway, G. A. Carlson, C. Bergeron… in Prions and Brain Diseases in Animals and H… (1998)