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    Chapter and Conference Paper

    Signifikante EGF Rezeptor Inhibition und anhaltende antineoplastische Wirkung durch Matuzumab Kurzzeittherapie (EMD72000) im experimentellen Pankreaskarzinom

    In unseren Experimenten hemmt Matuzumab (EMD72000) durch Blockade der EGFR Phosphorylierung nachweislich die MAPK-Proliferationskaskade in vitro und zeigt eine signifikante antiproliferative, antiangiogene und an...

    Dr. A. Kleespies, O. Mantell, C. Amendt, M. Yezhelyev, M. Guba… in Chirurgisches Forum 2006 (2006)

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    Article

    Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development

    The role of Transforming growth factor beta (TGF-β) in carcinogenesis is complex. There are reports on both tumor inhibition and tumor promotion by TGF-β. To elucidate the complex role of TGF-β in epithelial c...

    C Amendt, P Schirmacher, H Weber, M Blessing in Oncogene (1998)