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Article
Ex vivo expansion of CD34+/CD41+ late progenitors from enriched peripheral blood CD34+ cells
In our experience, patients with neuroblastoma who undergo transplantation with CD34+ cells following high-dose chemotherapy have prolonged delays in platelet recovery. In vitro expansion of megakaryocyte (MK...
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Article
Kinetics of hematopoietic progenitor cell release induced by G-CSF-alone in children with solid tumors and leukemias
The kinetics of peripheral blood progenitor cell (PBPC) release induced by G-CSF-alone at 10 μg/kg/day were monitored daily in 42 children with solid tumors and leukemias. Median 16- and 27-fold enrichment of ...
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Article
Feasibility of a PB CD34+ cell transplantation procedure using standard leukapheresis products in very small children
To evaluate the feasibility and efficacy of CD34+ cell immunoselection from routine peripheral blood stem cell (PBSC) harvests in very small children a prospective study was performed in 15 children with advanced...