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Article
Open AccessPathways to adverse pregnancy outcomes: exploring the mediating role of intimate partner violence and depression: results from a South African rape cohort study
Adverse pregnancy outcomes (APOs) are common occurrences that contribute to negative maternal and child health outcomes. Our aim was to test the hypothesis that trauma exposure and depression are drivers of th...
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Article
Open AccessAssociations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa
This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covar...
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Article
Open AccessElevated resting heart rate is associated with several cardiovascular disease risk factors in urban-dwelling black South Africans
This study determined the associations of resting heart rate (RHR) with cardiovascular disease risk factors (CVDRF) in 25–74-year-old black South Africans. This cross-sectional study determined CVDRF by admini...
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Chapter
Tracing Natural Organic Matter at the Scale of Drainage Basins
Natural organic matter in soils contains stable semiquinone radicals, the nature of which depends on their origin and their maturation state. The relative proportions of these radicals, deduced from simulation...
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Article
Open AccessHeavy+light chain monitoring correlates with clinical outcome in multiple myeloma patients
Novel anti-myeloma agents have improved patient response rates, which are historically based on reductions of the M-protein. These methods can be inaccurate for quantifying M-proteins at low concentrations. We...
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Article
G-protein-coupled receptor kinase 4 polymorphisms predict blood pressure response to dietary modification in Black patients with mild-to-moderate hypertension
Dopamine via G-protein-coupled receptor kinase 4 (GRK-4) regulates sodium (Na) balance in the proximal tubule of the kidney. Single-nucleotide polymorphisms of GRK-4 have been linked to impaired natriuresis an...
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Article
Proteinase 3 hydrolysis of peptides derived from human elastin exon 24
In normal and pathological tissues, elastin-derived peptides proceed of elastin degradation by polymorphonuclear leukocyte proteases: elastase, cathepsin G and proteinase 3. They were demonstrated to have a ch...
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Article
Blood pressure and social support observations from Mamre, South Africa, during social and political transition
Objective: Social support, by moderating cardiovascular reactivity, has been demonstrated to attenuate the effects of stress on blood pressure in American communities. This is the first report to examine the rela...
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Chapter
The Weekend Effect
Since the presence of any element in a urinary calculus suggests that it may have fulfilled some pathogenic role, the present study was undertaken to establish whether differences exist between stone formers (...
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Article
Das Göttinger Miniaturschwein als Versuchstier
The miniature swine is steadily gaining prominence as a laboratory animal. This paper attempts to survey the existing literature concerning the Göttinger Minipig and to give some information about breeding, gr...
