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Article
Physical and functional cooperation between AP-1 and β-catenin for the regulation of TCF-dependent genes
Stabilization of cytoplasmic β-catenin is a hallmark of a variety of cancers. The stabilized β-catenin is able to translocate to the nucleus, where it acts as a transcriptional activator of T-cell factor (TCF)-re...
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Article
The LIM-only protein FHL2 is a negative regulator of E4F1
The E1A-targeted transcription factor E4F1 is a key player in the control of mammalian embryonic and somatic cell proliferation and survival. Mouse embryos lacking E4F die at an early developmental stage, wher...