Skip to main content

19 Result(s)

within C L White Remove this filter Nanotechnology Remove this filter

and

  1. No Access

    Article

    Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery

    Transfer of healthy autologous tissue as a microvascular free flap facilitates reconstruction during ablative cancer surgery. In addition to filling surgical defects, free flaps might concentrate viral vectors...

    V K Agrawal, K M Copeland, Y Barbachano, A Rahim, R Seth, C L White… in Gene Therapy (2009)

  2. Article

    Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

    Reovirus is a promising unmodified double-stranded RNA (dsRNA) anti-cancer oncolytic virus, which is thought to specifically target cells with activated Ras. Although reovirus has been tested in a wide range o...

    F Errington, C L White, K R Twigger, A Rose, K Scott, L Steele, L J Ilett… in Gene Therapy (2008)

    Download PDF (979 KB) View Article

  3. No Access

    Article

    Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

    There is an emerging realization from animal models that the immune response may have both detrimental and beneficial therapeutic effects during cancer virotherapy. However, there is a dearth of clinical data ...

    C L White, K R Twigger, L Vidal, J S De Bono, M Coffey, L Heinemann… in Gene Therapy (2008)

  4. No Access

    Article

    Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo

    Escherichia coli nitroreductase (NTR) converts the prodrug CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide) into a bifunctional alkylating agent that causes DNA crosslinks. In this study, the ability of NTR to enh...

    C L White, T Menghistu, K R Twigger, P F Searle, S A Bhide, R G Vile… in Gene Therapy (2008)

  5. No Access

    Article

    Effects of Processing on Fiber/Matrix Interfaces in Ni3Al/Sapphire Single Crystal Composites

    Composites consisting of Ni3Al modified with Zr, Fe, and B (IC-50) reinforced with continuous sapphire single crystal fibers have been prepared by vacuum hot pressing foil/fiber multilayers. Previous research det...

    D. Ringer, C. L. White in MRS Online Proceedings Library (1994)

  6. No Access

    Article

    Foreword

    D. A. Smith, C. S. Pande, B. B. Rath, C. L. White in Metallurgical Transactions A (1990)

  7. No Access

    Article

    The Effect of Bulk Boron Level on its Segregation to Grain Boundaries in Substoichiometric Ni3Al

    It is well established that the grain boundary strength (and thus the ductility) of polycrystalline Ni3Al is a function of the level of boron segregated to su h boundaries. This paper presents some Auger Electron...

    Ashok Choudhury, C. L. White, C. R. Brooks in MRS Online Proceedings Library (1988)

  8. No Access

    Article

    Evaluation of the effects of segregation on austenite grain boundary energy in Fe-C-X alloys

    A scanning Auger microprobe study has been made of the segregation of substitutional alloying elements to austenite grain boundaries in Fe-C-X alloys (where X = Mn, Ni, Si, Co, and Mo). The grain boundary enri...

    M. Enomoto, C. L. White, H. I. Aaronson in Metallurgical Transactions A (1988)

  9. No Access

    Article

    The Segregation of Boron and Its Effect on the Fracture of An Ni3Si Based Alloy

    It is now well established that microalloying additions of B to Ni3Al drastically reduce low temperature grain boundary fracture and consequently increase the ductility of this intermetallic compound. One possibl...

    W. C. Oliver, C. L. White in MRS Online Proceedings Library (1986)

  10. No Access

    Article

    On the improvement of creep strength and ductility of Ni-20 pct Cr by small zirconium additions

    The creep and fracture properties of high-purity Ni-20 pct Cr and Ni-20 pct Cr-0.11 pct Zr alloys are compared at 1073 K in vacuum. The Ni-20 pct Cr alloy cavitates at the grain boundaries and fractures interg...

    J. H. Schneibel, C. L. White, M. H. Yoo in Metallurgical Transactions A (1985)

  11. No Access

    Article

    Weldability of Ni3Al-Type Aluminide Alloys

    If the ductile Ni3Al-based aluminides are to achieve their full potential as engineering materials, they must demonstrate a capability for being joined by conventional welding processes. The goal of this study wa...

    M. L. Santella, S. A. David, C. L. White in MRS Online Proceedings Library (1984)

  12. No Access

    Article

    Design of Ductile Polycrystalline Ni3Al Alloys

    This paper provides a comprehensive review of current efforts on design of ductile polycrystalline Ni3Al alloys. Microalloying has proven to be very effective in alleviating the grain-boundary emibrittlement prob...

    C. T. Liu, C. L. White in MRS Online Proceedings Library (1984)

  13. No Access

    Article

    The Role of Trace Elements and Interfaces in Creep Failure

    C. L. White, M. H. Yoo in Metallurgical Transactions A (1983)

  14. No Access

    Article

    High temperature embrittlement of NI and Ni-Cr alloys by trace elements

    The effects of Sb, Sn, and Zr additions on the creep properties of Ni and Ni + 20 pct Cr are reported. Antimony and tin additions (~1 wt pct) induce extensive grain boundary cavitation in nickel, while smaller...

    C. L. White, J. H. Schneibel, R. A. Padgett in Metallurgical Transactions A (1983)

  15. No Access

    Article

    Boron Segregation to Grain Boundaries and Improved Ductility in Pt + 30 Wt Pct Rh + 8WtPctW

    Boron additions of up to 75 wt ppm have been observed to improve the room temperature strength and ductility of a Pt + 30 wt pct Rh + 8 wt pct W alloy. Alloys without boron fail intergranularly, and those with...

    C. L. White, J. R. Keiser, D. N. Braski in Metallurgical Transactions A (1981)

  16. No Access

    Article

    On the mechanism of intergranular embrittlement by phosphorus in transformer steel

    Transformer steel (Fe-6 at. pct Si) was doped with varying amounts of phosphorus and given an embrittling step-cool heat treatment. Auger electron spectroscopy was used to determine that large increases in int...

    R. G. Thompson, C. L. White, J. J. Wert, D. S. Easton in Metallurgical Transactions A (1981)

  17. No Access

    Article

    Sulfur segregation to grain boundaries in Ni3Al and Ni3(AI,Ti) alloys

    The segregation of S to grain boundaries in Ni3Al and Ni3(Al, Ti) has been studied using Auger electron spectroscopy. The S concentration at the grain boundaries decreases more slowly with increasing temperature ...

    C. L. White, D. F. Stein in Metallurgical Transactions A (1978)

  18. No Access

    Article

    The spectrum of binding energies approach to grain boundary segregation

    C. L. White, W. A. Coghlan in Metallurgical Transactions A (1977)

  19. No Access

    Article

    Influence of crystallography on aspects of solid-solid nucleation theory

    Expressions for the major variables in the general rate equation for solid-solid nucleation were developed on the basis of various models of the critical nucleus shape during homogeneous and heterogeneous nucl...

    W. C. Johnson, C. L. White, P. E. Marth, P. K. Ruf… in Metallurgical Transactions A (1975)