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    IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T cell-mediated tumor rejection in the context of a systemic Th2 response

    In spite of the evidence that IL-10 has Th1-immunosuppressive and anti-inflammatory effects, it has been shown that IL-10 may reduce the tumorigenic capacity of certain tumor cell types. In order to characteri...

    S K Adris, S Klein, M A Jasnis, E Chuluyan, M F Ledda, A I Bravo, C Carbone… in Gene Therapy (1999)