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Article
How long does it take to diagnose young-onset dementia? A comparison with late-onset dementia
Dementia occurring in young people may be difficult to recognize. We compared the time to diagnosis between young- (YOD, age < 65) and late-onset dementia (LOD).
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Article
Open AccessNew insights into vitamin D regulation: is there a role for alkaline phosphatase?
The diagnosis of vitamin D deficiency is based on the determination of total plasma 25-hydroxyvitamin D (25-OHD) concentrations, but the regulation of vitamin D 25-hydroxylation is not a major consideration an...
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Article
Open AccessTransition from unclassified Ktedonobacterales to Actinobacteria during amorphous silica precipitation in a quartzite cave environment
The orthoquartzite Imawarì Yeuta cave hosts exceptional silica speleothems and represents a unique model system to study the geomicrobiology associated to silica amorphization processes under aphotic and stabl...
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Article
Sexual dysfunctions in young women with type 1 diabetes and high glucose variability: findings from the METRO study
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Article
Open AccessTopologization of β-antimonene on Bi2Se3 via proximity effects
Topological surface states usually emerge at the boundary between a topological and a conventional insulator. Their precise physical character and spatial localization depend on the complex interplay between t...
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Article
Uveal melanoma: physiopathology and new in situ-specific therapies
Uveal melanoma is the most common primary intraocular tumor in adults. It can arise from melanocytes in the anterior (iris) or posterior uveal tract (choroid and ciliary body). Uveal melanoma has a particular ...
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Article
Open AccessAdipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling
Solid epidemiological evidences connect obesity with incidence, stage and survival in pancreatic cancer. However, the underlying mechanistic basis linking adipocytes to pancreatic cancer progression remain lar...
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Chapter and Conference Paper
Measuring the Universe with Galaxy Redshift Surveys
Galaxy redshift surveys are one of the pillars of the current standard cosmological model and remain a key tool in the experimental effort to understand the origin of cosmic acceleration. To this end, the next...
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Article
Effect of temperature on the release and remobilization of ecotoxic elements in AMD colloidal precipitates: the example of the Libiola copper mine, Liguria, (Italy)
Due to their characteristics, colloidal particles are able to control the dispersion of many organic and inorganic pollutants in soils and streams. Colloidal precipitates generated by acid mine drainage (AMD) ...
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Article
Open AccessTAK1-regulated expression of BIRC3 predicts resistance to preoperative chemoradiotherapy in oesophageal adenocarcinoma patients
About 20% of resectable oesophageal carcinoma is resistant to preoperative chemoradiotherapy. Here we hypothesised that the expression of the antiapoptotic gene Baculoviral inhibitor of apoptosis repeat contai...
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Article
Low-radiation environment affects the development of protection mechanisms in V79 cells
Very little is known about the influence of environmental radiation on living matter. In principle, important information can be acquired by analysing possible differences between parallel biological systems, ...
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Article
Mineralogical and chemical variations of ochreous precipitates from acid sulphate waters (asw) at the Roşia Montană gold mine (Romania)
The mineralogical and chemical variations of ochreous precipitates forming from acid sulphate waters discharged from the lowest mine adit (“Sf. Cruci din Orlea”) of the Roşia Montană Gold Mine (Romania) were i...
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Article
Erratum: Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells
Correction to: Cell Death and Disease (2013) 4, e641; doi:10.1038/cddis.2013.165; published online 23 May 2013 Since the publication of this paper the authors have noticed the blots in Figure 5c displaying p-P...
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Article
Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT
There is conflicting evidence on the predictive role of KRAS status when cetuximab is added to oxaliplatin-based regimens. This study investigated the impact of KRAS, NRAS, BRAF, PI3KCA and TP53 status on outcome...
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Article
A new inclusion complex of amlodipine besylate and soluble β-cyclodextrin polymer: preparation, characterization and dissolution profile
Amlodipine besylate (AML) has become the most popular blood pressure medication for hypertensive pets. It belongs to the class I (high solubility and high permeability) according to BCS and is marketed in Euro...
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Article
Open AccessAcquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells
The nitrogen-containing bisphosphonates (N-BP) zoledronic acid (ZOL) inhibits osteoclast-mediated bone resorption, and it is used to prevent skeletal complications from bone metastases. ZOL has also demonstrat...
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Article
Open AccessClinical phenotype of neonatal lupus erythematosus relates to autoantibody level and gender
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Article
Open AccessAnalysis of growth in female patients with pediatric-onset systemic lupus erythematosus
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Article
Mineralogical and geochemical characterisation of open-air tailing and waste-rock dumps from the Libiola Fe-Cu sulphide mine (Eastern Liguria, Italy)
Active acid mine drainage (AMD) processes at the Libiola Fe-Cu sulphides mine are mainly triggered by water–rock interaction occurring within open-air tailing and waste-rock dumps. These processes are mainly c...
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Chapter and Conference Paper
The Stochastic Gravitational-Wave Background from Cold Dark Matter Halos
