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  1. Article

    Open Access

    TAK1-regulated expression of BIRC3 predicts resistance to preoperative chemoradiotherapy in oesophageal adenocarcinoma patients

    About 20% of resectable oesophageal carcinoma is resistant to preoperative chemoradiotherapy. Here we hypothesised that the expression of the antiapoptotic gene Baculoviral inhibitor of apoptosis repeat contai...

    G Piro, S Giacopuzzi, M Bencivenga, C Carbone, G Verlato… in British Journal of Cancer (2015)

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  2. No Access

    Article

    Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT

    There is conflicting evidence on the predictive role of KRAS status when cetuximab is added to oxaliplatin-based regimens. This study investigated the impact of KRAS, NRAS, BRAF, PI3KCA and TP53 status on outcome...

    M. Di Bartolomeo, F. Pietrantonio, F. Perrone, K. F. Dotti, A. Lampis… in Targeted Oncology (2014)

  3. No Access

    Article

    IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T cell-mediated tumor rejection in the context of a systemic Th2 response

    In spite of the evidence that IL-10 has Th1-immunosuppressive and anti-inflammatory effects, it has been shown that IL-10 may reduce the tumorigenic capacity of certain tumor cell types. In order to characteri...

    S K Adris, S Klein, M A Jasnis, E Chuluyan, M F Ledda, A I Bravo, C Carbone… in Gene Therapy (1999)