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Article
Open AccessGlobal gene expression in muscle from fasted/refed trout reveals up-regulation of genes promoting myofibre hypertrophy but not myofibre production
Compensatory growth is a phase of rapid growth, greater than the growth rate of control animals, that occurs after a period of growth-stunting conditions. Fish show a capacity for compensatory growth after all...
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Article
Open AccessGene expression profile during proliferation and differentiation of rainbow trout adipocyte precursor cells
Excessive accumulation of adipose tissue in cultured fish is an outstanding problem in aquaculture. To understand the development of adiposity, it is crucial to identify the genes which expression is associate...
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Article
Open AccessGene expression profiling of the hyperplastic growth zones of the late trout embryo myotome using laser capture microdissection and microarray analysis
A unique feature of fish is that new muscle fibres continue to be produced throughout much of the life cycle; a process termed muscle hyperplasia. In trout, this process begins in the late embryo stage and occ...
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Article
Open AccessThe production of fluorescent transgenic trout to study in vitro myogenic cell differentiation
Fish skeletal muscle growth involves the activation of a resident myogenic stem cell population, referred to as satellite cells, that can fuse with pre-existing muscle fibers or among themselves to generate a ...
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Article
Open AccessDynamic gene expression in fish muscle during recovery growth induced by a fasting-refeeding schedule
Recovery growth is a phase of rapid growth that is triggered by adequate refeeding of animals following a period of weight loss caused by starvation. In this study, to obtain more information on the system-wid...
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Article
A NLRR-1 gene is expressed in migrating slow muscle cells of the trout (Oncorhynchus mykiss) embryo
NLRR-l (neuronal leucine-rich repeat-l) is a transmembrane protein that functions as a cell adhesion molecule regulating morphogenesis. A previous study in the mouse reported that the somitic expression of NLR...
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Article
Manipulation of the ubiquitin-proteasome pathway in cachexia: pentoxifylline suppresses the activation of 20S and 26S proteasomes in muscles from tumor-bearing rats
The development of pharmacological approaches for preventing the loss of muscle proteins would be extremely valuable for cachectic patients. For example, severe wasting in cancer patients correlates with a red...
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Article
Expression of subunits of the 19S complex and of the PA28 activator in rat skeletal muscle
A precise knowledge of the role of subunits of the 19S complex and the PA28 regulator, which associate with the 20S proteasome and regulate its peptidase activities, may contribute to design new therapeutic ap...
