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Article

Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies

Most targeted cancer therapies fail to achieve complete tumor regressions or attain durable remissions. To understand why these treatments fail to induce robust cytotoxic responses despite appropriately target...

Joan Montero, Cécile Gstalder, Daniel J. Kim, Dorota Sadowicz… in Nature Communications (2019)