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  1. No Access

    Article

    Toxicological evaluation of an apicidin derivative, histone deacetylase inhibitor SD-2007 in mice

    SD-2007 is a new derivative of apicidin, an anti-parasitic agent and a histone deacetylase (HDAC) inhibitor. A subacute toxicological evaluation of SD-2007 was investigated for 2 weeks in ICR mice. After oral ...

    Seung Jun Kwack, Kyu Bong Kim, Byung Mu Lee in Archives of Pharmacal Research (2009)

  2. No Access

    Article

    Anti-hypertensive effect of the dongchunghacho, isaria sinclairii, in the spontaneously hypertensive rats

    The present study examined the effect of the methanol extract ofIsaria sinclairii, a kind of Donchunghacho (Tochukaso), on blood pressure in spontaneously hypertensive rats (SHR). Blood pressure and heart rate we...

    Mi Young Ahn, Yi Sook Jung, Sang Deok Jee, Chan Shik Kim… in Archives of Pharmacal Research (2007)

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    Article

    Cytotoxicity and L-amino acid oxidase activity of animal venoms

    The cytotoxicity of animal venoms (snakes, insects and marine animals) was measured against SNU-1 (stomach cancer cells) by dye uptake assay (MTT method). And also L-amino acid oxidase (AAO) activity of the ve...

    Mi Young Ahn, Byung Mu Lee, Yeong Shik Kim in Archives of Pharmacal Research (1997)