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  1. Article

    Open Access

    Publisher Correction: Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs

    The original version of this Article contained an error in Fig. 1. In panel d, the model on the right of the panel was incorrectly labeled ‘+Heme’, and should have read ‘− Heme’. This has now been corrected in...

    Alexander C. Partin, Tri D. Ngo, Emily Herrell, Byung-Cheon Jeong… in Nature Communications (2018)

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  2. Article

    Open Access

    Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing

    The spindle checkpoint maintains genomic stability and prevents aneuploidy. Unattached kinetochores convert the latent open conformer of the checkpoint protein Mad2 (O-Mad2) to the active closed conformer (C-M...

    Melissa L. Brulotte, Byung-Cheon Jeong, Faxiang Li, Bing Li… in Nature Communications (2017)

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  3. Article

    Open Access

    Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs

    MicroRNAs regulate the expression of many proteins and require specific maturation steps. Primary microRNA transcripts (pri-miRs) are cleaved by Microprocessor, a complex containing the RNase Drosha and its pa...

    Alexander C. Partin, Tri D. Ngo, Emily Herrell, Byung-Cheon Jeong… in Nature Communications (2017)

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  4. No Access

    Article

    MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling

    Mitsugumin 53 (MG53) negatively regulates skeletal myogenesis by targeting insulin receptor substrate 1 (IRS-1). Here, we show that MG53 is an ubiquitin E3 ligase that induces IRS-1 ubiquitination with the hel...

    Jae-Sung Yi, Jun Sub Park, Young-Mi Ham, Nga Nguyen, Na-Rae Lee… in Nature Communications (2013)