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    Reciprocal Effects of α-Synuclein Overexpression and Proteasome Inhibition in Neuronal Cells and Tissue

    Defects in the 20S/26S proteasome and conformational changes in α-synuclein (α-syn) are implicated in the development of sporadic and familial cases of PD. The objective of this study was to evaluate whether α...

    Melanie Dyllick-Brenzinger, Cheryl A. D’Souza, Burkhardt Dahlmann in Neurotoxicity Research (2010)