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  1. Article

    Open Access

    Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice

    Amyloid plaques and neurofibrillary tangles (NFTs) are the defining pathological hallmarks of Alzheimer’s disease (AD). Increasing the quantity of the O-linked N-acetylglucosamine (O-GlcNAc) post-translational mo...

    Scott A Yuzwa, **aoyang Shan, Bryan A Jones, Gang Zhao… in Molecular Neurodegeneration (2014)

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