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  1. No Access

    Article

    Progressive predominance of ‘skeletal’ versus ‘cardiac’ types of excitation-contraction coupling during in vitro skeletal myogenesis

    Simultaneous recordings, in the presence or absence of cadmium, of current and contraction of skeletal muscle cells in primary culture (myoballs) showed that the relative part of contraction depending on calci...

    Christian Cognard, Michèle Rivet-Bastide, Bruno Constantin, Guy Raymond in Pflügers Archiv (1992)

  2. No Access

    Article

    Activation of a slow outward current by the calcium released during contraction of cultured rat skeletal muscle cells

    A slow outward current, activated during depolarization, which induced contraction in whole-cell patch-clamped rat skeletal muscle cells in primary culture [10], was extensively characterized in the present st...

    Bruno Constantin, Christian Cognard, Michèle Rivet-Bastide, Guy Raymond in Pflügers Archiv (1993)

  3. No Access

    Article

    Differential interaction and activation of Rho family GTPases by p210bcr-abl and p190bcr-abl

    The p210bcr-abl and p190bcr-abl fusion proteins, respectively responsible for chronic myelogenous leukemia and acute lymphoblastic leukemia, present deregulated tyrosine kinase activity and abnormal localization....

    Thomas Harnois, Bruno Constantin, Agnès Rioux, Eddy Grenioux, Alain Kitzis… in Oncogene (2003)

  4. No Access

    Article

    New insights in the regulation of calcium transfers by muscle dystrophin-based cytoskeleton: implications in DMD

    Calcium mishandling in Duchenne muscular dystrophy (DMD) suggested that dystrophin, a membrane-associated cytoskeleton protein, may regulate calcium-signalling cascades such as calcium entries. Calcium overloa...

    Bruno Constantin, Stéphane Sebille… in Journal of Muscle Research & Cell Motility (2006)

  5. No Access

    Article

    Regulation by scaffolding proteins of canonical transient receptor potential channels in striated muscle

    Recent studies proposed a pivotal role of TRPC channels, in particular TRPC1, in the striated muscle tissue and in the development of calcium mishandling observed in dystrophin-deficient skeletal and cardiac m...

    J. Sabourin, C. Cognard, Bruno Constantin in Journal of Muscle Research and Cell Motility (2009)

  6. No Access

    Chapter

    Role of Scaffolding Proteins in the Regulation of TRPC-Dependent Calcium Entry

    Plasma membrane ion channels, and in particular TRPC channels need a specific membrane environment and association with scaffolding, signaling, and cytoskeleton proteins in order to play their important functi...

    Bruno Constantin in Calcium Entry Pathways in Non-excitable Cells (2016)

  7. No Access

    Article

    Constitutive calcium entry and cancer: updated views and insights

    Tight control of basal cytosolic Ca2+ concentration is essential for cell survival and to fine-tune Ca2+-dependent cell functions. A way to control this basal cytosolic Ca2+ concentration is to regulate membrane ...

    Olivier Mignen, Bruno Constantin, Marie Potier-Cartereau… in European Biophysics Journal (2017)