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Neurological toxicities of targeted therapies in melanoma: a multicenter national observational study of the French Group of Skin Cancers (Groupe de Cancérologie Cutanée, GCC)
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Article
Machine learning algorithm to predict response to immunotherapy in real-life settings for patients with advanced melanoma
Melanoma is one of the most fatal forms of skin cancer. Defining relevant biomarkers to predict treatment outcome based on immune checkpoint inhibitors (ICIs) is needed in order to increase overall survival of...
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Article
Open AccessEvaluation of Psychological Wellbeing and Social Impact of Combined Facial and Truncal Acne: a Multi-national, Mixed-Methods Study
Half of the individuals with facial acne develop truncal acne, but the impact of combined facial and truncal acne (CA) on patients’ quality of life is poorly researched.
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Article
Adapalene/benzoyl peroxide gel 0.3%/2.5% for acne vulgaris
Acne vulgaris is typically treated with a combination of a topical retinoid plus an antimicrobial agent, as recommended by national and international evidence-based guidelines around the globe. Adapalene, a sy...
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Article
Advocacy for a shared physician/patient approach for the management of acne, rosacea, seborrheic dermatitis and photodamage
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Article
Open AccessImpact of Facial Atrophic Acne Scars on Quality of Life: A Multi-country Population-Based Survey
Acne affects more than 80% of adolescents and young adults, who most often develop acne scars. Supporting data on the effect of acne scars on patient’s health-related quality of life (HRQOL) are limited.
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Article
Open AccessKey Clinical Adverse Events in Patients with Advanced Basal Cell Carcinoma Treated with Sonidegib or Vismodegib: A Post Hoc Analysis
Sonidegib is approved to treat locally advanced basal cell carcinoma (laBCC) in the USA, EU, Switzerland, and Australia and metastatic basal cell carcinoma (mBCC) in Switzerland and Australia in patients not a...
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Article
Open AccessPhase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients
Adoptive cell transfer (ACT) of tumor-specific T lymphocytes represents a relevant therapeutic strategy to treat metastatic melanoma patients. Ideal T-cells should combine tumor specificity and reactivity with...
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Article
Open AccessAcne Scarring: Why We Should Act Sooner Rather Than Later
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Article
COVID-19 hand hygiene measures for health care workers
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Article
Complete spontaneous regression of primary Merkel cell carcinoma with tumoural infiltration: a systematic review
Merkel cell carcinoma (MCC) is an aggressive tumour that rapidly evolves to metastasis, however, paradoxically, complete spontaneous regression (CSR) of MCC has been reported. CSR may be linked to the presence...
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Chapter
Update on Cutibacterium acnes
Acne is one of the most common skin inflammatory diseases, representing the top three most prevalent skin conditions in the general population worldwide (Johnson and Roberts, Vital Health Stat 11 (212):i–v, 1–...
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Article
Open AccessThe Skin Microbiome: A New Actor in Inflammatory Acne
Our understanding of the role of Cutibacterium acnes in the pathophysiology of acne has recently undergone a paradigm shift: rather than C. acnes hyperproliferation, it is the loss of balance between the differen...
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Open AccessForeword
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Article
Open AccessImpact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with dacarbazine or vemurafenib ± cobimetinib: a pooled analysis of four clinical trials
We sought to identify patient subgroups with distinct postprogression overall survival (ppOS) outcomes and investigate the impact of original treatment assignment and initial postprogression treatment (ppRx) o...
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Article
Tumor infiltrating lymphocytes as adjuvant treatment in stage III melanoma patients with only one invaded lymph node after complete resection: results from a multicentre, randomized clinical phase III trial
Adoptive tumor-infiltrating lymphocytes (TIL) therapy and interleukin-2 (IL-2) have been investigated in melanoma.
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Article
Management of adjuvant settings for Stage III melanoma patients in France prior to checkpoint inhibitors: epidemiological data from the RIC-Mel database
Targeted therapies such as BRAF and MEK inhibitors and immunotherapies have been made available to treat melanoma.
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Article
Open AccessFASCE, the benefit of spironolactone for treating acne in women: study protocol for a randomized double-blind trial
Acne vulgaris has increased in women over the past 10 years; it currently affects 20–30% of women. The physiopathology of adult female acne is distinguished from that of teenagers essentially by two factors: h...
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Article
Open AccessTranscriptomic features of tumour-infiltrating CD4lowCD8high double positive αβ T cells in melanoma
Peripheral CD4+CD8+ double positive (DP) T cells are a phenotypically and functionally heterogeneous population depending on their origin and pathologic context. We previously identified among tumour infiltrating...
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Article
Open AccessCICAFAST: comparison of a biological dressing composed of fetal fibroblasts and keratinocytes on a split-thickness skin graft donor site versus a traditional dressing: a randomized controlled trial
Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dress...
