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Article
Open AccessThe single-cell opioid responses in the context of HIV (SCORCH) consortium
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One of th...
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Article
Open AccessAuthor Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse
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Article
Open AccessComparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals1. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 ...
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Article
Open AccessA transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased samples of the diverse cell types in the brain1–3. With the proliferation of multi-omics datasets, a major challenge i...
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Article
Open AccessDefense against territorial intrusion is associated with DNA methylation changes in the honey bee brain
Aggression is influenced by individual variation in temperament as well as behavioral plasticity in response to adversity. DNA methylation is stably maintained over time, but also reversible in response to spe...
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Article
Reversible switching between epigenetic states in honeybee behavioral subcastes
This paper reports that there are substantial differences in DNA methylation patterns between nurses and forager caste phenotypes in honeybees, and that reverting foragers back to nurses reestablishes methylat...
