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    Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi

    The oncoprotein Smoothened (SMO), a G-protein-coupled receptor (GPCR) of the Frizzled-class (class-F), transduces the Hedgehog signal from the tumour suppressor Patched-1 (PTCH1) to the glioma-associated-oncog...

    **aofeng Qi, Heng Liu, Bonne Thompson, Jeffrey McDonald, Cheng Zhang, **aochun Li in Nature (2019)