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  1. Article

    Open Access

    Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites

    The mechanisms by which parkin protects the adult human brain from Parkinson disease remain incompletely understood. We hypothesized that parkin cysteines participate in redox reactions and that these are refl...

    Jacqueline M. Tokarew, Daniel N. El-Kodsi, Nathalie A. Lengacher in Acta Neuropathologica (2021)

  2. Article

    Open Access

    Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

    Braak and Del Tredici have proposed that typical Parkinson disease (PD) has its origins in the olfactory bulb and gastrointestinal tract. However, the role of the olfactory system has insufficiently been explo...

    Julianna J. Tomlinson, Bojan Shutinoski, Li Dong in Journal of Neural Transmission (2017)