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  1. Article

    Erratum to: A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

    Jianxin Dai, Bohua Li, **** Shi, Ling Peng… in Cancer Immunology, Immunotherapy (2010)

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    A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

    Osteopontin (OPN) has been implicated as an important mediator of breast cancer progression and metastasis and has been investigated for use as a potential therapeutic target in the treatment of breast cancer....

    Jianxin Dai, Bohua Li, **** Shi, Ling Peng… in Cancer Immunology, Immunotherapy (2010)

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    Article

    PE38KDEL-loaded anti-HER2 nanoparticles inhibit breast tumor progression with reduced toxicity and immunogenicity

    The clinical use of Pseudomonas exotoxin A (PE)-based immunotoxins is limited by the toxicity and immunogenicity of PE. To overcome the limitations, we have developed PE38KDEL-loaded poly(lactic-co-glycolic acid)...

    Jie Gao, Geng Kou, Hao Wang, Huaiwen Chen, Bohua Li… in Breast Cancer Research and Treatment (2009)

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    Treatment of hepatocellular carcinoma in a mouse xenograft model with an immunotoxin which is engineered to eliminate vascular leak syndrome

    Vascular leak syndrome (VLS) is the major dose-limiting toxicity of immunotoxin and interleukin-2 therapy. It has been evidenced that VLS-inducing molecules share a three-amino acid consensus motif, (x)D(y), w...

    Hao Wang, Shuichuan Song, Geng Kou, Bohua Li… in Cancer Immunology, Immunotherapy (2007)

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    Eradication of hepatoma and colon cancer in mice with Flt3L gene therapy in combination with 5-FU

    We developed a recombinant defective adenovirus with an insert of gene encoding extracellular domain of mouse Flt3L (Ad-mFlt3L) under control of cytomegalovirus promoter to investigate the biological efficacy ...

    Sheng Hou, Geng Kou, **aoqiang Fan, Hao Wang… in Cancer Immunology, Immunotherapy (2007)