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2,103 Result(s)
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Open AccessA systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
Robot-assisted minimally invasive gastrectomy (RAMIG) is increasingly used as a surgical approach for gastric cancer. This study assessed the effectiveness of RAMIG and studied which stages of the IDEAL-framew...
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Open AccessGemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients
Fanconi anemia (FA) is a rare hereditary disease resulting from an inactivating mutation in the FA/BRCA pathway, critical for the effective repair of DNA interstrand crosslinks (ICLs). The disease is character...
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Open AccessStudy Protocol: Pegasus: psychotherapy incorporating horses for ‘therapy-resistant’ adolescents with autism spectrum disorders, a study with series of randomised, baseline controlled n-of-1 trials
For people with autism spectrum disorder (ASD), daily life can be highly stressful with many unpredictable events that can evoke emotion dysregulation (ED): a strong difficulty with appropriately negative affe...
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Open AccessA complete chromosome substitution map** panel reveals genome-wide epistasis in Arabidopsis
Chromosome substitution lines (CSLs) are tentatively supreme resources to investigate non-allelic genetic interactions. However, the difficulty of generating such lines in most species largely yielded imperfec...
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Open AccessShort and long-term acceptability and efficacy of extended-release cornstarch in the hepatic glycogen storage diseases: results from the Glyde study
Hypoglycaemia is the primary manifestation of all the hepatic types of glycogen storage disease (GSD). In 2008, Glycosade®, an extended-release waxy maize cornstarch, was reported as an alternative to uncooked co...
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Open AccessLet’s talk about work: pilot study of an education program on discussing work participation with cancer patients for general practitioners in training
Cancer patients report that they lack support from healthcare providers when it comes to returning to or maintaining employment. In the education of general practitioners (GPs) in the Netherlands, there is lit...
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Open AccessIntegration of genetics and MRD to define low risk patients with B-cell precursor acute lymphoblastic leukaemia with intermediate MRD levels at the end of induction
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Open AccessPage curves and replica wormholes from random dynamics
We show how to capture both the non-unitary Page curve and replica wormhole-like contributions that restore unitarity in a toy quantum system with random dynamics. The motivation is to find the simplest dynami...
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Open AccessAuthor Correction: Prediction of recurrence risk in endometrial cancer with multimodal deep learning
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Open AccessNFL and GFAP in (pre)symptomatic RVCL-S carriers: a monogenic cerebral small vessel disease
Neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) have emerged as biomarkers for cerebral small vessel disease (SVD). We investigated their role in a hereditary SVD model, retinal vasc...
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Open AccessModel matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)
In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeu...
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Open AccessReducing sectoral hard-to-abate emissions to limit reliance on carbon dioxide removal
To reach net-zero greenhouse gas targets, carbon dioxide removal (CDR) technologies are required to compensate for residual emissions in the hard-to-abate sectors. However, dependencies on CDR technologies inv...
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Open AccessDemonstration and Analysis of Conditions to Obtain a High Strength Inconel 625 to Stainless Steel 304L Interface by Directed Energy Deposition
Functional grading (FG) is often used to bond dissimilar metals. However, that approach is complicated from a manufacturing perspective, and the associated challenges can outweigh the benefits of FG. Here, we ...
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Open AccessAn atypical case of fatal ‘esophageal apoplexy’: post-mortem findings and differential diagnosis
Forensic pathologists need to have comprehensive knowledge of a large variety of causes of sudden natural death. We describe a case of sudden and unexpected death in woman in her sixties due to rupture of a la...
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Open AccessPredicting the bodily self in space and time
To understand how the human brain distinguishes itself from external stimulation, it was examined if motor predictions enable healthy adult volunteers to infer self-location and to distinguish their body from ...
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Geschlechterspezifische Aspekte kardiovaskulärer Erkrankungen
Kardiovaskuläre Erkrankungen sind weltweit sowohl bei Männern als auch bei Frauen die führende Todesursache. Durch fokussierte klinische und wissenschaftliche Untersuchungen hat sich das Verständnis für geschl...
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Open AccessThe possible impact of segmenting radiological images on students’ spatial abilities
Visuospatial ability plays a crucial role in anatomy related study success as studies have shown that students with high scores on a mental rotation test (MRT) perform better on anatomy exams. We hypothesized ...
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Open AccessBacteriophage ISP eliminates Staphylococcus aureus in planktonic phase, but not in the various stages of the biofilm cycle
Metal-implant associated bacterial infections are a major clinical problem due to antibiotic treatment failure. As an alternative, we determined the effects of bacteriophage ISP on clinical isolates of Staphyloco...
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Open AccessNegotiating becoming: a Nietzschean critique of large language models
Large language models (LLMs) structure the linguistic landscape by reflecting certain beliefs and assumptions. In this paper, we address the risk of people unthinkingly adopting and being determined by the val...
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Open AccessAmplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay
The resonant structure of the radiative decay Λ b 0 ...