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  1. Article

    Open Access

    Effects of nitrogen availability on polymalic acid biosynthesis in the yeast-like fungus Aureobasidium pullulans

    Polymalic acid (PMA) is a novel polyester polymer that has been broadly used in the medical and food industries. Its monomer, L-malic acid, is also a potential C4 platform chemical. However, little is known ab...

    Yongkang Wang, **aodan Song, Yongjun Zhang, Bochu Wang in Microbial Cell Factories (2016)

  2. Article

    Open Access

    Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release

    Nanotechnology-based drug delivery systems have been widely used for oral and systemic dosage forms delivery depending on the mucoadhesive interaction, and keratin has been applied for biomedical applications ...

    Zhongjun Cheng, **aoliang Chen, Dongliang Zhai, Feiyan Gao in Journal of Nanobiotechnology (2018)

  3. No Access

    Article

    Comparative transcriptome analysis of the fungus Gibberella zeae transforming lithocholic acid into ursodeoxycholic acid

    The comparative transcriptome analysis of the fungus Gibberella zeae which could efficiently catalyze the 7β-hydroxylation of LCA to produce UDCA was performed with LCA induction. This is the first time to report...

    Biling Yang, Renfen Zha, Wenyan Zhao, Daoyong Gong, **nhua Meng in Biotechnology Letters (2021)

  4. No Access

    Article

    Modifying the Microenvironment of Epoxy Resin to Improve the Activity of Immobilized 7α-Hydroxysteroid Dehydrogenases

    7α-Hydroxysteroid dehydrogenase (7α-HSDH) is one of the key enzymes in the catalytic reaction of taurochenodeoxycholic acid (TCDCA). To improve the activity of immobilized 7α-HSDH, the microenvironment of immo...

    Qiong Yang, Liuying Li, Bochu Wang, Liancai Zhu in Applied Biochemistry and Biotechnology (2021)

  5. Article

    Open Access

    Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl

    Dendrobium nobile Lindl. has been used as a traditional Chinese medicine for a long time, in which the most important compound is dendrobine functioning in a variety of pharmacological activities. Farnesyl diphos...

    Daoyong Gong, Bin Wu, Hongting Qin, Dezhao Fu, Shunxing Guo, Bochu Wang in AMB Express (2022)