3 Result(s)
within
Bo-xin Xue
Biochemistry, general
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Article
Open AccessTargeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth
Sphingosine kinases (SphK), including SphK1 and SphK2, are important enzymes promoting progression of prostate cancer. SKI-178 is a novel and highly potent SphK1/2 dual inhibitor. We here tested the potential ...
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Article
Open AccessGNE-493 inhibits prostate cancer cell growth via Akt-mTOR-dependent and -independent mechanisms
GNE-493 is a novel PI3K/mTOR dual inhibitor with improved metabolic stability, oral bioavailability, and excellent pharmacokinetic parameters. Here GNE-493 potently inhibited viability, proliferation, and migr...
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Article
Isolation and passage of muscle-derived stem cells from the rat penile corpora cavernosa and induction of differentiation into smooth muscle cells
This study treated the isolation and passage of muscle-derived stem cells (MDSCs) from rat penile corpora cavernosa, detection of stem cell marker expression, observation of their self-renewal and continuous p...
