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  1. Article

    Open Access

    Targeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth

    Sphingosine kinases (SphK), including SphK1 and SphK2, are important enzymes promoting progression of prostate cancer. SKI-178 is a novel and highly potent SphK1/2 dual inhibitor. We here tested the potential ...

    Lu **, ** Zhu, Linya Yao, Gang Shen, Bo-xin Xue, Wei Tao in Cell Death & Disease (2023)

  2. Article

    Open Access

    A case report of acute testicular pain secondary to segmental testicular infarction

    Segmental testicular infarction is a rare condition that often occurs in the upper pole of the left testicle and usually presents with acute onset of scrotal pain. Contrast-enhanced ultrasound and MR are essen...

    Hong-Liang **, Qi Ma, ** Zhu, Ya-Chen Zang, Yi-Bin Zhou, Bo-**n Xue in BMC Urology (2022)

  3. Article

    Open Access

    GNE-493 inhibits prostate cancer cell growth via Akt-mTOR-dependent and -independent mechanisms

    GNE-493 is a novel PI3K/mTOR dual inhibitor with improved metabolic stability, oral bioavailability, and excellent pharmacokinetic parameters. Here GNE-493 potently inhibited viability, proliferation, and migr...

    Lu **, Wei Zhang, Ming-Yu Yao, Ye Tian, Bo-xin Xue, Wei Tao in Cell Death Discovery (2022)

  4. No Access

    Article

    Photoselective vaporization of the prostate with GreenLight 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis of randomized controlled trials

    The aim of this study is to assess the overall efficacy and safety of photoselective vaporization of the prostate (PVP) with GreenLight 120-W laser versus transurethral resection of the prostate (TURP) for tre...

    Ya-Chen Zang, **n-** Deng, Dong-Rong Yang, Bo-**n Xue in Lasers in Medical Science (2016)

  5. No Access

    Article

    Oncolytic virus carrying shRNA targeting SATB1 inhibits prostate cancer growth and metastasis

    Recent studies suggest that SATB1 is a promising therapeutic target for prostate cancer. To develop novel SATB1-based therapeutic agents for prostate cancer, in this study, we aimed to construct ZD55-SATB1, an...

    Li-jun Mao, Jie Zhang, Ning Liu, Li Fan, Dong-rong Yang, Bo-xin Xue in Tumor Biology (2015)

  6. No Access

    Article

    Subcapsular renal hematoma after ureteroscopy with holmium:yttrium-aluminum-garnet laser lithotripsy

    Subcapsular renal hematoma (SRH) after ureteroscopic lithotripsy (URSL) using holmium:yttrium-aluminum-garnet (Ho:YAG) laser to treat ureteric stones is a rare complication. We aimed to review our unit’s exper...

    Wei Tao, Chun Jie Cai, Chuan Yang Sun, Bo **n Xue, Yu ** Shan in Lasers in Medical Science (2015)

  7. No Access

    Article

    Isolation and passage of muscle-derived stem cells from the rat penile corpora cavernosa and induction of differentiation into smooth muscle cells

    This study treated the isolation and passage of muscle-derived stem cells (MDSCs) from rat penile corpora cavernosa, detection of stem cell marker expression, observation of their self-renewal and continuous p...

    Li-Jun Xu, Bo-**n Xue, Dong Chen, Jie Gao, Dong-Rong Yang, Chuan-Yang Sun in Cytotechnology (2014)