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Article

Targeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth

Sphingosine kinases (SphK), including SphK1 and SphK2, are important enzymes promoting progression of prostate cancer. SKI-178 is a novel and highly potent SphK1/2 dual inhibitor. We here tested the potential ...

Lu **, ** Zhu, Linya Yao, Gang Shen, Bo-xin Xue, Wei Tao in Cell Death & Disease (2023)