23 Result(s)

Article

Early combination therapy of COVID-19 in high-risk patients

Prolonged shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been observed in immunocompromised hosts. Early monotherapy with direct-acting antivirals or monoclonal antibodies, as rec...

Hans Martin Orth, Charlotte Flasshove, Moritz Berger, Tessa Hattenhauer… in Infection (2024)

Article

Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV-2 variants delta and omicron—results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP)

The influence of new SARS-CoV-2 variants on the post-COVID-19 condition (PCC) remains unanswered. Therefore, we examined the prevalence and predictors of PCC-related symptoms in patients infected with the SARS...

Sina M. Hopff, Katharina S. Appel, Olga Miljukov, Johannes Schneider… in Infection (2024)

Article

Hemophagocytic lymphohistiocytosis—how common and how severe is it as a complication of malaria? Retrospective case series and review of the literature

Infection-associated secondary hemophagocytic lymphohistiocytosis (sHLH) is a potentially life-threatening hyperinflammatory condition caused by various infectious diseases. Malaria has rarely been described a...

Hans Martin Orth, Dorothea Wiemer, Sophie Schneitler, Andreas Schönfeld… in Infection (2024)

Article

AIDS-defining events among people living with HIV who have been under continuous antiretroviral therapy for more than one year, a German cohort study 1999–2018

This study examined the characteristics, incidence and prognostic factors of the first AIDS-defining condition developed after more than one year of continuous antiretroviral therapy (ART) among people living ...

Annemarie Pantke, Christian Kollan, Barbara Gunsenheimer-Bartmeyer… in Infection (2024)

Article

Erratum zu: OMW: HIV Postexpositionsprophylaxe in der Notaufnahme. Wann einleiten?

Nora Dehina, Björn-Erik Ole Jensen, Michael Bernhard… in Notfall + Rettungsmedizin (2024)

Article

HIV-Postexpositionsprophylaxe in der Notaufnahme: Vorgehen, Tipps & Tricks

In zentralen Notaufnahmen stellen sich regelmäßig Patienten nach vermutetem oder gesichertem Kontakt mit dem humanen Immundefizienzvirus (HIV) vor, um dort bezüglich der Indikation einer Postexpositionsprophyl...

Nora Dehina, Björn-Erik Ole Jensen… in Notfall + Rettungsmedizin (2023)

Article

EuCARE-hospitalised study protocol: a cohort study of patients hospitalised with COVID-19 in the EuCARE project

Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), can lead to hospitalisation, particularly in elderly, immunocompromised, and non-vac...

Pontus Hedberg, Benedetta Varisco, Francesca Bai… in BMC Infectious Diseases (2023)

Article

Tecovirimat for the treatment of severe Mpox in Germany

In May 2022, a multi-national mpox outbreak was reported in several non-endemic countries. The only licensed treatment for mpox in the European Union is the orally available small molecule tecovirimat, which in O...

Lennart Hermanussen, Thomas Theo Brehm, Timo Wolf, Christoph Boesecke… in Infection (2023)

Article

OMW: HIV Postexpositionsprophylaxe in der Notaufnahme. Wann einleiten?

Lennert Böhm, Nora Dehina, Björn-Erik Ole Jensen… in Notfall + Rettungsmedizin (2023)

Article

Use and effectiveness of remdesivir for the treatment of patients with covid-19 using data from the Lean European Open Survey on SARS-CoV-2 infected patients (LEOSS): a multicentre cohort study

The use of remdesivir (RDV) as the first drug approved for coronavirus disease 2019 (COVID-19) remains controversial. Based on the Lean European Open Survey on severe acute respiratory syndrome coronavirus-2 (...

Lisa Pilgram, Katharina S. Appel, Maria M. Ruethrich, Carolin E. M. Koll… in Infection (2023)

Article

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Despite scientific evidence originating from two patients published to date that CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) can cure human immunodeficiency virus type 1 (HIV-1), the knowledge o...

Björn-Erik Ole Jensen, Elena Knops, Leon Cords, Nadine Lübke… in Nature Medicine (2023)

Article

Percutaneous fractionated radiotherapy of the groin to eliminate lymphatic fistulas after vascular surgery

Vascular surgery of the inguinal area can be complicated by persistent lymphatic fistulas. Rapid and effective treatment is essential to prevent infection, sepsis, bleeding, and possible leg amputation. Curren...

Danny Jazmati, Bálint Tamaskovics… in European Journal of Medical Research (2023)

Article

Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection

The presentation of peptides and the subsequent immune response depend on the MHC characteristics and influence the specificity of the immune response. Several studies have found an association between HLA var...

Johannes C. Fischer, Vera Balz, Danny Jazmati… in European Journal of Medical Research (2022)

Article

Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients

Metabolic disorders have been identified as major risk factors for severe acute courses of COVID-19. With decreasing numbers of infections in many countries, the long COVID syndrome (LCS) represents the next m...

Sven H. Loosen, Björn-Erik Ole Jensen, Christian Tanislav, Tom Luedde… in Infection (2022)

Article

Recurrent parvovirus B19 viremia resulting in two episodes of hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory condition with uncontrolled activation of lymphocytes and macrophages. Besides a primary (genetic) form, HLH can also be triggered by malignant, ...

Hans Martin Orth, Andre Fuchs, Nadine Lübke, Björn-Erik Ole Jensen… in Virology Journal (2022)

Article

Acute cardiac side effects after COVID-19 mRNA vaccination: a case series

Vaccination against SARS-CoV-2 has been the main tool to contain the pandemic. The rush development of the 3 vaccines and their expedited approval have led to inoculation of millions of patients around the wor...

Noemi F. Freise, Milena Kivel, Olaf Grebe… in European Journal of Medical Research (2022)

Article

Correction to: Multicentric Castleman’s disease in HIV patients: a single-center cohort diagnosed from 2008 to 2018

A correction to this paper has been published: https://doi.org/10.1007/s15010-021-01627-4

Smaranda Gliga, Hans Martin Orth, Nadine Lübke, Jörg Timm, Tom Luedde… in Infection (2021)

Article

Multicentric Castleman’s disease in HIV patients: a single-center cohort diagnosed from 2008 to 2018

Castleman’s disease (CD) is a well-established entity but there is a lack of available data regarding the management and therapy of HIV- and HHV-8-positive multicentric CD (MCD). We provide our own single-cent...

Smaranda Gliga, Hans Martin Orth, Nadine Lübke, Jörg Timm, Tom Luedde… in Infection (2021)

Article

Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction

The coronavirus disease 2019 (COVID‐19) is associated with a wide clinical spectrum of skin manifestations, including urticarial, vesicular, vasculitic and chilblain‐like lesions. Recently, delayed skin reacti...

Norman-Philipp Hoff, Noemi F. Freise… in European Journal of Medical Research (2021)