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  1. Article

    Open Access

    Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer

    Human telomeres are linked to genetic instability and a higher risk of develo** cancer. Therefore, to improve the dismal prognosis of pancreatic cancer patients, a thorough investigation of the association b...

    Shengyang Chen, Shuiquan Hu, Baizhong Zhou, Bingbing Cheng, Hao Tong in Scientific Reports (2023)

  2. Article

    Open Access

    The effect of transcranial focused ultrasound target location on the acoustic feedback control performance during blood-brain barrier opening with nanobubbles

    Real-time acoustic feedback control based on harmonic emissions of stimulated microbubbles may be important for facilitating the clinical adoption of focused ultrasound (FUS)-induced blood-brain barrier (BBB) ...

    Bingbing Cheng, Chenchen Bing, Rajiv Chopra in Scientific Reports (2019)

  3. Article

    Open Access

    Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control

    Focused ultrasound combined with bubble-based agents serves as a non-invasive way to open the blood-brain barrier (BBB). Passive acoustic detection was well studied recently to monitor the acoustic emissions i...

    Chenchen Bing, Yu Hong, Christopher Hernandez, Megan Rich in Scientific Reports (2018)

  4. Article

    Open Access

    Employing high-frequency alternating magnetic fields for the non-invasive treatment of prosthetic joint infections

    Treatment of prosthetic joint infection (PJI) usually requires surgical replacement of the infected joint and weeks of antibiotic therapy, due to the formation of biofilm. We introduce a non-invasive method fo...

    Rajiv Chopra, Sumbul Shaikh, Yonatan Chatzinoff, Imalka Munaweera in Scientific Reports (2017)

  5. Article

    Open Access

    New generation ICG-based contrast agents for ultrasound-switchable fluorescence imaging

    Recently, we developed a new technology, ultrasound-switchable fluorescence (USF), for high-resolution imaging in centimeter-deep tissues via fluorescence contrast. The success of USF imaging highly relies on ...

    Shuai Yu, Bingbing Cheng, Tingfeng Yao, Cancan Xu, Kytai T. Nguyen in Scientific Reports (2016)

  6. Article

    Open Access

    High resolution imaging beyond the acoustic diffraction limit in deep tissue via ultrasound-switchable NIR fluorescence

    Fluorescence imaging in deep tissue with high spatial resolution is highly desirable because it can provide details about tissue's structural, functional and molecular information. Unfortunately, current fluor...

    Yanbo Pei, Ming-Yuan Wei, Bingbing Cheng, Yuan Liu, Zhiwei **e in Scientific Reports (2014)