10 Result(s)

Article

Correction: Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials

Dan-Ya Wu, **nxin Li, Qiao-Ran Sun, Cheng-Li Dou, Tian Xu… in Cell Death & Disease (2021)

Article

Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials

Nuclear transfer embryonic stem cells (ntESCs) hold enormous promise for individual-specific regenerative medicine. However, the chromatin states of ntESCs remain poorly characterized. In this study, we employ...

Dan-Ya Wu, **nxin Li, Qiao-Ran Sun, Cheng-Li Dou, Tian Xu… in Cell Death & Disease (2021)

Article

EVR: reconstruction of bacterial chromosome 3D structure models using error-vector resultant algorithm

More and more 3C/Hi-C experiments on prokaryotes have been published. However, most of the published modeling tools for chromosome 3D structures are targeting at eukaryotes. How to transform prokaryotic experi...

Kang-Jian Hua, Bin-Guang Ma in BMC Genomics (2019)

Article

Genomic analyses of primitive, wild and cultivated citrus provide insights into asexual reproduction

Qiang Xu and colleagues sequence four citrus species de novo, along with 100 accessions, including primitive, wild and cultivated citrus. Their genomic analyses associate the CitRWP gene with polyembryony and sug...

**a Wang, Yuantao Xu, Siqi Zhang, Li Cao, Yue Huang, Junfeng Cheng… in Nature Genetics (2017)

Article

A novel proposal of a simplified bacterial gene set and the neo-construction of a general minimized metabolic network

A minimal gene set (MGS) is critical for the assembly of a minimal artificial cell. We have developed a proposal of simplifying bacterial gene set to approximate a bacterial MGS by the following procedure. Fir...

Yuan-Nong Ye, Bin-Guang Ma, Chuan Dong, Hong Zhang, Ling-Ling Chen… in Scientific Reports (2016)

Article

Abundance and Temperature Dependency of Protein-Protein Interaction Revealed by Interface Structure Analysis and Stability Evolution

Protein complexes are major forms of protein-protein interactions and implement essential biological functions. The subunit interface in a protein complex is related to its thermostability. Though the roles of...

Yi-Ming He, Bin-Guang Ma in Scientific Reports (2016)

Article

Amino Acid Flux from Metabolic Network Benefits Protein Translation: the Role of Resource Availability

Protein translation is a central step in gene expression and affected by many factors such as codon usage bias, mRNA folding energy and tRNA abundance. Despite intensive previous studies, how metabolic amino a...

**ao-Pan Hu, Yi Yang, Bin-Guang Ma in Scientific Reports (2015)

Article

Spatial features for Escherichia coli genome organization

In bacterial genomes, the compactly encoded genes and operons are well organized, with genes in the same biological pathway or operons in the same regulon close to each other on the genome sequence. In additio...

Ting **e, Liang-Yu Fu, Qing-Yong Yang, Heng **ong, Hongrui Xu, Bin-Guang Ma… in BMC Genomics (2015)

Article

Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery

Extant life depends greatly on the binding of small molecules (such as ligands) with macromolecules (such as proteins), and one ligand can bind multiple proteins. However, little is known about the global patt...

Hong-Fang Ji, De-**n Kong, Liang Shen, Ling-Ling Chen, Bin-Guang Ma… in Genome Biology (2007)