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    Article

    Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria

    The marine alkaloid ascididemin (ASC) was shown to exert cytotoxicity even against multidrug-resistant cancer cells. Here, we address the signaling pathways utilized by ASC to trigger apoptosis in Jurkat leuke...

    Verena M Dirsch, Stephanie O Kirschke, Michael Estermeier, Bert Steffan… in Oncogene (2004)

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    Article

    Pigmentation and tunic cells in Cystodytes dellechiajei (Urochordata, Ascidiacea)

    The tunic of Cystodytes dellechiajei (Poly- citoridae), a colony-forming species of the Ascidiacea that contains biologically active alkaloids, was investigated using light microscopy, laser-scanning microscopy a...

    Eva-Maria Rottmayr, Bert Steffan, G. Wanner in Zoomorphology (2001)

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    Article

    1H-Nuclear Magnetic Resonance (NMR) Studies on the Inclusion Complex of Prostaglandin El (PGE1 with α-Cyclodextrin

    Prostaglandin El is currently marketed as a freeze-dried injectable inclusion complex with α-cyclodextrin for the treatment of peripheral arterial diseases. α-Cyclodextrin is used as a stabilizing agent and to im...

    Bert Steffan, Wilfried Fischer, Günther Cordes, Ilona Habon… in Pharmaceutical Research (1992)