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  1. Article

    Open Access

    Gene expression profiling of brain endothelial cells after experimental subarachnoid haemorrhage

    Subarachnoid haemorrhage (SAH) is a type of hemorrhagic stroke that is associated with high morbidity and mortality. New effective treatments are needed to improve outcomes. The pathophysiology of SAH is compl...

    Michael K. Tso, Paul Turgeon, Bert Bosche, Charles K. Lee, Tian Nie… in Scientific Reports (2021)

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    Article

    Complex Clearance Mechanisms After Intraventricular Hemorrhage and rt-PA Treatment—a Review on Clinical Trials

    Intracerebral hemorrhage in combination with intraventricular hemorrhage (IVH) is a severe type of stroke frequently leading to prolonged clinical care, continuous disability, shunt dependency, and high mortal...

    Bert Bosche, Philipp Mergenthaler, Thorsten R. Doeppner… in Translational Stroke Research (2020)

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    Article

    Spontaneous subdural hematomas particularly with a decreased coagulation factor XIII activity require follow-ups of the neuroradiological diagnostic

    Bert Bosche, Bastian Kraus, Marek Molcanyi in Neuroradiology (2017)

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    Article

    Conditioned Medium Derived from Neural Progenitor Cells Induces Long-term Post-ischemic Neuroprotection, Sustained Neurological Recovery, Neurogenesis, and Angiogenesis

    Adult neural progenitor cells (NPCs) induce post-ischemic long-term neuroprotection and brain remodeling by releasing of survival- and plasticity-promoting mediators. To evaluate whether secreted factors may m...

    Thorsten R. Doeppner, Viktorija Traut, Alexander Heidenreich… in Molecular Neurobiology (2017)

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    Article

    Evoked Potentials in Acute Ischemic Stroke within the First 24 h: Possible Predictor of a Malignant Course

    In patients with large middle cerebral artery (MCA) infarction, space-occupying brain edema may lead to a malignant course with up to 80% mortality, under conservative treatment. As interventional treatment st...

    Lothar Burghaus, Wei-Chi Liu, Christian Dohmen, Bert Bosche… in Neurocritical Care (2008)