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Open AccessImproving tumor budding reporting in colorectal cancer: a Delphi consensus study
Tumor budding is a long-established independent adverse prognostic marker in colorectal cancer, yet methods for its assessment have varied widely. In an effort to standardize its reporting, a group of experts ...
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Early esophageal squamous cell carcinoma in a western series is not associated with active HPV infection
Few data are available concerning human papillomavirus (HPV) in early esophageal squamous cell carcinoma (ESCC) in Western population. Our study intended to determine the prevalence of HPV infection and the hi...
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Sostdc1 is expressed in all major compartments of develo** and adult mammalian eyes
This study was conducted in order to study Sostdc1 expression in rat and human develo** and adult eyes.
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Article
Open AccessEarly-onset liver cancer in South America associates with low hepatitis B virus DNA burden
In Peru, hepatocellular carcinoma (HCC) arises in young non-cirrhotic patients. Hepatitis B virus (HBV) is suspected to be the prominent etiological agent. We thus performed a comprehensive molecular study of ...
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Intraductal acinar cell carcinoma of the pancreas
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Pancreatic Involvement in Von Hippel-Lindau Disease
Von Hippel-Lindau (VHL) disease is characterized by a dominant autosomal predisposition to develop hemangioblastomas of the retina and central nervous system (CNS), renal cell carcinoma, pheochromocytoma and e...
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Intraductal acinar cell carcinoma of the pancreas
We describe a purely intraductal acinar cell carcinoma involving branch ducts of the pancreas in a 74-year-old man, which presented as recurrent episodes of acute pancreatitis. Endoscopic ultrasound examinati...
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Article
Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients
To discriminate among the chromosomal abnormalities associated with the etiology of hepatocellular carcinoma (HCC), we performed a comparative genomic hybridization (CGH) analysis on 34 HCCs resected on non-ci...
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Close correlation between β-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas
Several lines of evidence indicate that β-catenin acquires oncogenic activity when its intracellular concentration increases as a result of either mutation in the β-catenin gene itself or inactivation of the a...
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Squamous cell carcinoma and lipomatous pseudohypertrophy of the pancreas
A 68-year-old woman who had been treated for non-insulin-dependent diabetes mellitus for the past 20 years was admitted to hospital because of abdominal pain and weight loss. Radiological investigation reveal...